Introduction:-
Scrub typhus is a zoonotic rickettsiosis caused by the bacterium
Orientia tsutsugamushi. It is transmitted by larvae of the
Leptotrombidium mites and is endemic to a region called the
tsutsugamushi triangle that extends from Southeast Asia to the Pacific
Ocean 1. Scrub typhus commonly infects farmers and
field workers 1. The central nervous system (CNS) can
often be affected in scrub typhus, with neurological manifestations
being present in approximately 20% of cases, either in the form of
acute encephalitis, meningitis, or meningoencephalitis2. The clinical manifestations of scrub typhus are
variable, with the involvement of nearly every system and organ, alone
or in combination 3. Recent epidemiological studies
suggest that scrub typhus is a major cause of central nervous system
infections in endemic areas 4–6. The neurological
manifestation of scrub typhus has become an emerging public health
concern beyond current endemic areas, as ecological changes may increase
the prevalence of arthropod-borne CNS-infected populations worldwide7. On the other hand, delayed treatment can lead to
significant neurological creaks and even death 8.