STRING analysis
Protein-protein interaction networks were produced using STRING ver.
11.0 [35]
(https://string-db.org/) for
important groups of significant proteins, including those significantly
regulated in all treatments. Lists of accession numbers for these
significant proteins were entered in the search function “multiple
proteins”, creating network maps and enrichment values as
over-representation of network nodes (proteins) with high or low FC in
STRING functional clusters, Uniprot keywords, and Pfam, InterPro, or
SMART protein domains with a false discovery rate (FDR) <0.05
after correcting for multiple testing using the Benjamini-Hochberg
procedure.