References
Baumeister, D., Akhtar, R., Ciufolini, S., Pariante, C.M. & Mondelli, V. (2016) Childhood trauma and adulthood inflammation: a meta-analysis of peripheral C-reactive protein, interleukin-6 and tumour necrosis factor-a. Mol. Psychiatry , 21 , 642–649.
Berlim, M.T. & Turecki, G. (2007) Definition, assessment, and staging of treatment-resistant refractory major depression: A review of current concepts and methods. Canad. J. Psychiatry, 52 , 46-54.
Beurel, E., Toups, M. & Nemeroff, C.B. (2020) The bidirectional relationship of depression and inflammation: double trouble.Neuron , 107 , 234-256.
Binder, E.B., Salyakina, D., Lichtner, P., Wochnik, G.M., Ising, M., Pütz, B., Papiol, S., Seaman, S., Lucae, S., Kohli, M.A., Nickel, T., Künzel, H.E., Fuchs, B., Majer, M., Pfennig, A., Kern, N., Brunner, J., Modell, S., Baghai, T., Deiml, T., Zill, P., Bondy, B., Rupprecht, R., Messer, T., Köhnlein, O., Dabitz, H., Brückl, T., Müller, N., Pfister, H., Lieb, R., Mueller, J.C., Lõhmussaar, E., Strom, T.M., Bettecken, T., Meitinger, T., Uhr, M., Rein, T., Holsboer, F. & Muller-Myhsok, B. (2004) Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.Nat. Genet. , 36 , 1319–1325.
Cheng, Z., Su, J., Zhang, K., Jiang, H. & Li, B. (2022) Epigenetic mechanism of early life stress-induced depression: focus on the neurotransmitter systems. Front. Cell. Dev. Biol. , 10 , 929732.
Criado-Marrero, M., Smith, T.M., Gould, L.A., Kim, S., Penny, H.J., Sun, Z., Gulick, D., Dickey, C.A. & Blair, L.J. (2020) FKBP5 and early life stress affect the hippocampus by an age-dependent mechanism. Brain Behav. Immun. Health , 17 , 100143.
David, D.J. & Gourion, D. (2016) Antidépresseurs et tolérance: déterminants et prise en charge des principaux effets indésirables [Antidepressant and tolerance: Determinants and management of major side effects]. Encephale , 42 , 553-561.
de Kloet, E., Joëls, M. & Holsboer, F. (2005) Stress and the brain: from adaptation to disease. Nat. Rev. Neurosci. , 6 , 463–475.
Gan, Y.L., Wang, C.Y., He, R.H., Hsu, P.C., Yeh, H.H., Hsieh, T.H., Lin, H.C., Cheng, M.Y., Jeng, C.J., Huang, M.C. & Lee, Y.H. (2022) FKBP51 mediates resilience to inflammation-induced anxiety through regulation of glutamic acid decarboxylase 65 expression in mouse hippocampus.J. Neuroinflamm. , 19 , 152.
Gong, T., Liu, L., Jiang, W. & Zhou, R. (2020) DAMP-sensing receptors in sterile inflammation and inflammatory diseases. Nat. Rev. Immunol. , 20 , 95-112.
Grogans, S.E., Fox, A.S. & Shackman, A.J. (2022) The amygdala and depression: A sober reconsideration. Am. J. Psychiatry ,179 , 454-457.
Häusl, A.S., Brix, L.M., Hartmann, J., Pöhlmann, M.L., Lopez, J.P., Menegaz, D., Brivio, E., Engelhardt, C., Roeh, S., Bajaj, T., Rudolph, L., Stoffel, R., Hafner, K., Goss, H.M., Reul, J.M.H.M., Deussing, J.M., Eder, M., Ressler, K.J., Gassen, N.C., Chen, A. & Schmidt MV. (2021) The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. Mol. Psychiatry , 26 , 3060–3076.
Ising, M., Horstmann, S., Kloiber, S., Lucae, S., Binder, E.B., Kern, N., Künzel, H.E., Pfennig, A., Uhr, M. & Holsboer, F. (2007) Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression – a potential biomarker? Biol. Psychiatry , 62 , 47-54.
Kang, H.J., Kawasawa, Y.I., Cheng, F., Zhu, Y., Xu, X., Li, M., Sousa, A.M.M., Pletikos, M., Meyer, K.A., Sedmak, G., Guennel, T., Shin, Y., Johnson, M.B., Krsnik, Z., Mayer, S., Fertuzinhos, S., Umlauf, S., Lisgo, S.N., Vortmeyer, A., Weinberger, D.R., Mane, S., Hyde, T.M., Huttner, A., Reimers, M., Kleinman, J.E. & Šestan N (2011) Spatio-temporal transcriptome of the human brain. Nature ,478 , 483–489.
Laine, M.A., Trontti, K., Misiewicz, Z., Sokolowska, E., Kulesskaya, N., Heikkinen, A., Saarnio, S., Balcells, I., Ameslon, P., Greco, D., Mattila, P., Ellonen, P., Paulin, L., Auvinen, P., Jokitalo, E. & Hovatta, I. (2018) Genetic control of myelin plasticity after chronic psychosocial stress. eNeuro , 5 , ENEURO.0166-18.2018.
Lekman, M., Laje, G., Charney, D., Rush, A.J., Wilson, A.F., Sorant, A.J., Lipsky, R., Wisniewski, S.R., Manji, H., McMahon, F.J. & Paddock, S. (2008) The FKBP5-gene in depression and treatment response - an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. Biol. Psychiatry , 63 , 1103-1110.
Lowe, S. (2023) cbrewer2 (https://github.com/scottclowe/cbrewer2), GitHub. Retrieved January 12, 2023.
Matosin, N., Arloth, J., Czamara, D., Edmond, K.Z., Maitra, M., Fröhlich, A.S., Martinelli, S., Kaul, D., Bartlett, R., Curry, A.R., Gassen, N.C., Hafner, K., Müller, N.S., Worf, K., Rehawi, G., Nagy, C., Halldorsdottir, T., Cruceanu, C., Gagliardi, M,, Gerstner, N., Ködel, M., Murek, V., Ziller, M.J., Scarr, E., Tao, R., Jaffe, A.E., Arzberger, T., Falkai, P., Kleinmann, J.E., Weinberger, D.R., Mechawar, N., Schmitt, A., Dean, B., Turecki, G., Hyde, T.M. & Binder, E.B. (2023) Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. Acta Neuropathol. , 145 , 439-459.
Menke, A., Klengel, T., Rubel, J., Brückl, T., Pfister, H., Lucae, S., Uhr, M., Holsboer, F. & Binder, E.B. (2013) Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression. Genes, Brain and Behavior , 12 , 289-296.
Menke, A., Nitschke, F., Hellmuth, A., Helmel, J., Wurst, C., Stonawski, S., Blickle, M., Weiß, C., Weber, H., Hommers, L., Domschke, K. & Deckert, J. (2021) Stress impairs response to antidepressants via HPA axis and immune system activation. Brain Behav. Immun. ,93 , 132-140.
Nanni, V., Uher, R. & Danese, A. (2012) Childhood maltreatment predicts unfavorable course of illness and treatment oucome in depression: a met-analysis. Am. J. Psychiatry , 169 ,141–151.
O’Leary, J.C.3rd, Dharia, S., Blair, L.J., Brady, S., Johnson, A.G., Peters, M., Cheung-Flynn, J., Cox, M.B., de Erausquin, G., Weeber, E.J., Jinwal, U.K. & Dickey, C.A. (2011) A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51. PLoS One , 6 , e24840.
Pizzagalli, D.A. & Roberts, A.C. (2022) Prefrontal cortex and depression. Neuropsychopharmacology , 47 , 225-246.
Raison, C.L., Capuron, L. & Miller, A.H. (2006) Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol. , 27 , 24-31.
Rubino, V. & Bozzi, Y. (2021) A new tool to implement gene expression data analysis from the Allen Brain Atlas: a practical outcome of a developmental neuroscience Master’s class. Neuroscience ,468 , 377–378.
Safran, M., Rosen, N., Twik, M., BarShir, R., Iny Stein, T., Dahary, D., Fishilevich, S. & Lancet, D. (2022) The GeneCards suite. In: Abugessaisa, I. & Kasukawa, T. (eds), Practical guide to life science databases . Springer, Singapore pp. 27-56.
Setiawan, E., Wilson, A.A., Mizrahi, R., Rusjan, P., Miler, L., Rajkowska, G., Suridjan, I., Kennedy, J.L., Rekkas, P.V., Houle, S. & Meyer, J.H. (2015) Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes.JAMA Psychiatry , 72 , 268–275.
Strawbridge, R., Arnone, D., Danese, A., Papadopoulos, A., Herane Vives, A. & Cleare, A.J. (2015) Inflammation and clinical response to treatment in depression: a meta-analysis. Eur. Neuropsychopharmacol ., 25 , 1532-1543.
Tao, R., Davis, K.N., Li, C., Shin, J.H., Gao, Y., Jaffe, A.E., Gondré-Lewis, M.C., Weinberger, D.R., Kleinman, J.E. & Hyde, T.M. (2017) GAD1 alternative transcripts and DNA methylation in human prefrontal cortex and hippocampus in brain development, schizophrenia.Mol. Psychiatry , 23 , 1496-1505.
Troubat, R., Barone, P., Leman, S., Desmidt, T., Cressant, A., Atanasova, B., Brizard, B., El Hage, W., Surget, A., Belzung, C. & Camus, V. (2021) Neuroinflammation and depression: a review. Eur. J. Neurosci. , 53 , 151-171.
Vermeer, H., Hendriks-Stegeman, B.I., van der Burg, B., van Buul-Offers, S.C. & Jansen, M. (2003) Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability. J. Clin. Endocrinol. Metab. , 88 , 277-284.
Vogelzangs, N., Beekman, A.T., van Reedt Dortland, A.K., Schoevers, R.A., Giltay, E.J., de Jonge, P. & Penninx, B.W. (2014) Inflammatory and metabolic dysregulation and the 2-year course of depressive disorders in antidepressant users. Neuropsychopharmacology ,39 ,1624-1634.
Wiechmann, T., Röh, S., Sauer, S., Czamara, D., Arloth, J., Ködel, M., Beintner, M., Knop, L., Menke, A., Binder, E.B. & Provençal, N. (2019) Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus. Clin. Epigenetics , 11 , 83.
Williams, L.M., Debattista, C., Duchemin, A.M., Schatzberg, A.F. & Nemeroff, C.B. (2016) Childhood trauma predicts antidepressant response in adults with major depression: data from the randomized international study to predict optimized treatment for depression. Transl. Psychiatry , 6 , e799.
Xu, J., Wang, R., Liu, Y., Wang, W., Liu, D., Jiang, H. & Pan, F. (2019) Short- and long-term alterations of FKBP5-GR and specific microRNAs in the prefrontal cortex and hippocampus of male rats induced by adolescent stress contribute to depression susceptibility.Psychoneuroendocrinology , 101 , 204-215.
Yeo, S., Enoch, M.A., Gorodetsky, E., Akhtar, L., Schuebel, K., Roy, A. & Goldman, D. (2017) The influence of FKBP5 genotype on expression of FKBP5 and other glucocorticoid-regulated genes, dependent on trauma exposure. Genes Brain Behav ., 16 , 223-232.
Zeier, Z., Carpenter, L.L., Kalin, N.H., Rodriguez, C.I., McDonald, W.M., Widge, A.S. & Nemeroff, C.B. (2018) Clinical implementation of pharmacogenetic decision support tools for antidepressant drug prescribing. Am. J. Psychiatry , 175 , 873–886.
Zhu, Y., Sousa, A.M.M., Gao, T., Skarica, M., Li, M., Santpere, G., Esteller-Cucala, P., Juan, D., Ferrández-Peral, L., Gulden, F.O., Yang, M., Miller, D.J., Marques-Bonet, T., Kawasawa, Y.I., Zhao, H. & Sestan, N. (2018) Spatiotemporal transcriptomic divergence across human and macaque brain development. Science , 362 , eaat8077.
Zobel, A., Schuhmacher, A., Jessen, F., Höfels, S., von Widdern, O., Metten, M., Pfeiffer, U., Hanses, C., Becker, T., Rietschel, M., Scheef, L., Block, W., Schild, H.H., Maier, W. & Schwab, S.G. (2010) DNA sequence variants of the FKBP5 gene are associated with unipolar depression. Int. J. Neuropsychopharmacol. , 13 , 649-660.