Data sources and searches
We conducted a comprehensive online search of the literature through the
Medline and EMBASE databases (to December 2022) to identify all
published clinical studies that compared outcomes of catheter ablation
of AF in young and old patients. To avoid missing relevant data, the
bibliographies of the reviewed manuscripts were manually retrieved. The
retrieval strategy used relevant keywords and medical subject heading
terms including the following: “pulmonary vein isolation”,“atrial
fibrillation”,“Radiofrequency catheter ablation”, “Cryoballoon
catheter ablation”,“Young adults”both separately and in combination.
The study and data collection were performed based on protocols approved
by the ethics committee of
The second affiliated hospital of nanchang university.