Data sources and searches
We conducted a comprehensive online search of the literature through the Medline and EMBASE databases (to December 2022) to identify all published clinical studies that compared outcomes of catheter ablation of AF in young and old patients. To avoid missing relevant data, the bibliographies of the reviewed manuscripts were manually retrieved. The retrieval strategy used relevant keywords and medical subject heading terms including the following: “pulmonary vein isolation”,“atrial fibrillation”,“Radiofrequency catheter ablation”, “Cryoballoon catheter ablation”,“Young adults”both separately and in combination. The study and data collection were performed based on protocols approved by the ethics committee of
The second affiliated hospital of nanchang university.