|
|
Pre-capillary PH (n=39) |
Pre-capillary PH (n=39) |
Post-capillary PH (n=59) |
Post-capillary PH (n=59) |
P |
Right heart chambers |
Right heart chambers |
Right heart chambers |
Right heart chambers |
|
|
|
Pulmonary Artery (mm) |
Pulmonary Artery (mm) |
28.26±5.0 |
28.26±5.0 |
27.15±5.63 |
27.15±5.63 |
0.452 |
RVFAC (%) |
RVFAC (%) |
31.28±10.06 |
31.28±10.06 |
34.30±9.10 |
34.30±9.10 |
0.143 |
S’ tricuspid valve (cm/s) |
S’ tricuspid valve (cm/s) |
13.00±3.65 |
13.00±3.65 |
12.32±3.17 |
12.32±3.17 |
0.359 |
PASP (mmHg) |
PASP (mmHg) |
70.54±19.88 |
70.54±19.88 |
67.22±15.25 |
67.22±15.25 |
0.303 |
TRV (m/s) |
TRV (m/s) |
3.84±0.58 |
3.84±0.58 |
3.74±0.48 |
3.74±0.48 |
0.245 |
PAMP (mmHg) |
PAMP (mmHg) |
49.97±13.18 |
49.97±13.18 |
47.95±9.69 |
47.95±9.69 |
0.351 |
Right Atrial Area (cm²) |
Right Atrial Area (cm²) |
17.72±4.72 |
17.72±4.72 |
18.86±6.38 |
18.86±6.38 |
0.793 |
TAPSE (mm) |
TAPSE (mm) |
19.28±3.89 |
19.28±3.89 |
19.08±4.04 |
19.08±4.04 |
0.81 |
TAPSE_PASP |
TAPSE_PASP |
0.30±0.10 |
0.30±0.10 |
0.30±0.09 |
0.30±0.09 |
0.82 |
Left Ventricular |
Left Ventricular |
|
|
|
|
|
LVEDI (mm) |
LVEDI (mm) |
28.80±5.89 |
28.80±5.89 |
35.06±6.33 |
35.06±6.33 |
<0.001 |
LVESI (mm) |
LVESI (mm) |
17.95±4.79 |
17.95±4.79 |
24.74±7.29 |
24.74±7.29 |
<0.001 |
LVEF (%) |
LVEF (%) |
68.90±7.07 |
68.90±7.07 |
55.31±15.50 |
55.31±15.50 |
<0.001 |
LVMI (g/m²) |
LVMI (g/m²) |
83.51±39.74 |
83.51±39.74 |
128.10±49.81 |
128.10±49.81 |
<0.001 |
E/e’ |
E/e’ |
9.32±3.14 |
9.32±3.14 |
20.59±10.55 |
20.59±10.55 |
<0.001 |
Left Atrial with 4D LAQ |
Left Atrial with 4D LAQ |
Left Atrial with 4D LAQ |
Left Atrial with 4D LAQ |
|
|
|
LAVImax(mL/m²) |
LAVImax(mL/m²) |
29.54±13.06 |
29.54±13.06 |
54.89±22.04 |
54.89±22.04 |
<0.001 |
LAVImin(mL/m²) |
LAVImin(mL/m²) |
16.26±8.57 |
16.26±8.57 |
36.75±17.65 |
36.75±17.65 |
<0.001 |
LAVIpreA(ml/m²) |
LAVIpreA(ml/m²) |
23.25±11.48 |
23.25±11.48 |
46.55±20.49 |
46.55±20.49 |
<0.001 |
DEI (%) |
DEI (%) |
0.45±0.11 |
0.45±0.11 |
0.34±0.12 |
0.34±0.12 |
<0.001 |
PEI (%) |
PEI (%) |
0.22±0.11 |
0.22±0.11 |
0.15±0.10 |
0.15±0.10 |
0.001 |
AEI (%) |
AEI (%) |
0.30±0.12 |
0.30±0.12 |
0.21±0.11 |
0.21±0.11 |
0.001 |
LASr (%) |
LASr (%) |
17.50±6.70 |
17.50±6.70 |
11.30±6.92 |
11.30±6.92 |
<0.001 |
LAScd(%) |
LAScd(%) |
-11.38±5.78 |
-11.38±5.78 |
-6.45±3.75 |
-6.45±3.75 |
<0.001 |
LASct (%) |
LASct (%) |
-8.50±3.71 |
-8.50±3.71 |
-7.0±4.42 |
-7.0±4.42 |
0.108 |
ePLAGS(m/s/%) |
ePLAGS(m/s/%) |
0.28±0.19 |
0.28±0.19 |
0.52±0.40 |
0.52±0.40 |
0.001 |
RVFAC:right ventricular fractional of area change; TRV: the maximum
velocity of Tricuspid valve regurgitation; TAPSE: tricuspid annular
plane systolic excursion. PASP and PAMP: pulmonary arterial systolic and
mean pressure; LVEDI, LVESI and LVMI: index of the left ventricular
diameters at the end of systole and diastole and left ventricular mass;
LVEF: left ventricular ejection fraction; LAVImax, LAVImin and LAVIpreA:
The indices of left atrial maximum volume, minimum volume and volume at
pre-ejection; DEI: LA storage function (diastolic ejection index); PEI:
LA channel function (passive ejection index); AEI: LA active systolic
function (active ejection index). LASr, LAScd and LASct: LA reservoir,
conduit and contraction strain; ePLAGS: the echocardiographic pulmonary
to LA global strain ratio. |
RVFAC:right ventricular fractional of area
change; TRV: the maximum velocity of Tricuspid valve regurgitation;
TAPSE: tricuspid annular plane systolic excursion. PASP and PAMP:
pulmonary arterial systolic and mean pressure; LVEDI, LVESI and LVMI:
index of the left ventricular diameters at the end of systole and
diastole and left ventricular mass; LVEF: left ventricular ejection
fraction; LAVImax, LAVImin and LAVIpreA: The indices of left atrial
maximum volume, minimum volume and volume at pre-ejection; DEI: LA
storage function (diastolic ejection index); PEI: LA channel function
(passive ejection index); AEI: LA active systolic function (active
ejection index). LASr, LAScd and LASct: LA reservoir, conduit and
contraction strain; ePLAGS: the echocardiographic pulmonary to LA global
strain ratio. |
RVFAC:right ventricular fractional of area change; TRV:
the maximum velocity of Tricuspid valve regurgitation; TAPSE: tricuspid
annular plane systolic excursion. PASP and PAMP: pulmonary arterial
systolic and mean pressure; LVEDI, LVESI and LVMI: index of the left
ventricular diameters at the end of systole and diastole and left
ventricular mass; LVEF: left ventricular ejection fraction; LAVImax,
LAVImin and LAVIpreA: The indices of left atrial maximum volume, minimum
volume and volume at pre-ejection; DEI: LA storage function (diastolic
ejection index); PEI: LA channel function (passive ejection index); AEI:
LA active systolic function (active ejection index). LASr, LAScd and
LASct: LA reservoir, conduit and contraction strain; ePLAGS: the
echocardiographic pulmonary to LA global strain ratio. |
RVFAC:right
ventricular fractional of area change; TRV: the maximum velocity of
Tricuspid valve regurgitation; TAPSE: tricuspid annular plane systolic
excursion. PASP and PAMP: pulmonary arterial systolic and mean pressure;
LVEDI, LVESI and LVMI: index of the left ventricular diameters at the
end of systole and diastole and left ventricular mass; LVEF: left
ventricular ejection fraction; LAVImax, LAVImin and LAVIpreA: The
indices of left atrial maximum volume, minimum volume and volume at
pre-ejection; DEI: LA storage function (diastolic ejection index); PEI:
LA channel function (passive ejection index); AEI: LA active systolic
function (active ejection index). LASr, LAScd and LASct: LA reservoir,
conduit and contraction strain; ePLAGS: the echocardiographic pulmonary
to LA global strain ratio. |
RVFAC:right ventricular fractional of area
change; TRV: the maximum velocity of Tricuspid valve regurgitation;
TAPSE: tricuspid annular plane systolic excursion. PASP and PAMP:
pulmonary arterial systolic and mean pressure; LVEDI, LVESI and LVMI:
index of the left ventricular diameters at the end of systole and
diastole and left ventricular mass; LVEF: left ventricular ejection
fraction; LAVImax, LAVImin and LAVIpreA: The indices of left atrial
maximum volume, minimum volume and volume at pre-ejection; DEI: LA
storage function (diastolic ejection index); PEI: LA channel function
(passive ejection index); AEI: LA active systolic function (active
ejection index). LASr, LAScd and LASct: LA reservoir, conduit and
contraction strain; ePLAGS: the echocardiographic pulmonary to LA global
strain ratio. |
RVFAC:right ventricular fractional of area change; TRV:
the maximum velocity of Tricuspid valve regurgitation; TAPSE: tricuspid
annular plane systolic excursion. PASP and PAMP: pulmonary arterial
systolic and mean pressure; LVEDI, LVESI and LVMI: index of the left
ventricular diameters at the end of systole and diastole and left
ventricular mass; LVEF: left ventricular ejection fraction; LAVImax,
LAVImin and LAVIpreA: The indices of left atrial maximum volume, minimum
volume and volume at pre-ejection; DEI: LA storage function (diastolic
ejection index); PEI: LA channel function (passive ejection index); AEI:
LA active systolic function (active ejection index). LASr, LAScd and
LASct: LA reservoir, conduit and contraction strain; ePLAGS: the
echocardiographic pulmonary to LA global strain ratio. |
RVFAC:right
ventricular fractional of area change; TRV: the maximum velocity of
Tricuspid valve regurgitation; TAPSE: tricuspid annular plane systolic
excursion. PASP and PAMP: pulmonary arterial systolic and mean pressure;
LVEDI, LVESI and LVMI: index of the left ventricular diameters at the
end of systole and diastole and left ventricular mass; LVEF: left
ventricular ejection fraction; LAVImax, LAVImin and LAVIpreA: The
indices of left atrial maximum volume, minimum volume and volume at
pre-ejection; DEI: LA storage function (diastolic ejection index); PEI:
LA channel function (passive ejection index); AEI: LA active systolic
function (active ejection index). LASr, LAScd and LASct: LA reservoir,
conduit and contraction strain; ePLAGS: the echocardiographic pulmonary
to LA global strain ratio. |
Table3 Univariate and multivariate modelling of parameters
differentiatng pre-capillary from post-capillary PH |
Table3 Univariate
and multivariate modelling of parameters differentiatng pre-capillary
from post-capillary PH |
Table3 Univariate and multivariate modelling of
parameters differentiatng pre-capillary from post-capillary PH |
Table3
Univariate and multivariate modelling of parameters differentiatng
pre-capillary from post-capillary PH |
Table3 Univariate and
multivariate modelling of parameters differentiatng pre-capillary from
post-capillary PH |
Table3 Univariate and multivariate modelling of
parameters differentiatng pre-capillary from post-capillary PH |
Table3
Univariate and multivariate modelling of parameters differentiatng
pre-capillary from post-capillary PH |
Variable |
Univariate analysis: OR (95% CI) |
Univariate analysis: OR
(95% CI) |
P |
P |
Multivariate analysis:OR (95% CI) |
Multivariate analysis:OR (95% CI) |
LAVImin |
1.16 (1.08, 1.25) |
1.16 (1.08, 1.25) |
<0.001 |
<0.001 |
|
|
LAVImax |
1.11 (1.05, 1.16) |
1.11 (1.05, 1.16) |
<0.001 |
<0.001 |
1.40 (1.05, 1.87) |
1.40 (1.05, 1.87) |
LAVIpreA |
1.12 (1.06, 1.18) |
1.12 (1.06, 1.18) |
<0.001 |
<0.001 |
0.72 (0.51, 1.01) |
0.72 (0.51,
1.01) |
LASr |
0.88 (0.82, 0.96) |
0.88 (0.82, 0.96) |
0.001 |
0.001 |
|
|
LAScd |
1.24 (1.08, 1.42) |
1.24 (1.08, 1.42) |
<0.001 |
<0.001 |
1.76 (1.18, 2.49) |
1.76 (1.18, 2.49) |
LASct |
1.31 (0.13, 6.60) |
1.31 (0.13, 6.60) |
0.273 |
0.273 |
|
|
ePLAGS |
38.06 (2.68, 539.68) |
38.06 (2.68, 539.68) |
0.007 |
0.007 |
|
|
DEI |
0.005(0.000, 0.333) |
0.005(0.000, 0.333) |
<0.001 |
<0.001 |
|
|
PEI |
0.05 (0.01, 0.39) |
0.05 (0.01, 0.39) |
0.014 |
0.014 |
|
|
AEI |
0.002 (0.00, 0.101) |
0.002 (0.00, 0.101) |
0.02 |
0.02 |
|
|
LVEDI |
1.19 (1.09, 1.29) |
1.19 (1.09, 1.29) |
<0.001 |
<0.001 |
|
|
LVEF |
0.91 (0.87, 0.95) |
0.91 (0.87, 0.95) |
<0.001 |
<0.001 |
|
|
LAVImax, LAVImin and LAVIpreA: The indices of left atrial maximum
volume, minimum volume and volume at pre-ejection; LASr, LAScd and
LASct: LA reservoir, conduit and contraction strain; ePLAGS: the
echocardiographic pulmonary to LA global strain ratio; DEI: LA storage
function (diastolic ejection index); PEI: LA channel function (passive
ejection index); AEI: LA active systolic function (active ejection
index); LVEDI: index of the left ventricular diameters at the end of
diastole; LVEF: left ventricular ejection fraction. |
LAVImax, LAVImin
and LAVIpreA: The indices of left atrial maximum volume, minimum volume
and volume at pre-ejection; LASr, LAScd and LASct: LA reservoir, conduit
and contraction strain; ePLAGS: the echocardiographic pulmonary to LA
global strain ratio; DEI: LA storage function (diastolic ejection
index); PEI: LA channel function (passive ejection index); AEI: LA
active systolic function (active ejection index); LVEDI: index of the
left ventricular diameters at the end of diastole; LVEF: left
ventricular ejection fraction. |
LAVImax, LAVImin and LAVIpreA: The
indices of left atrial maximum volume, minimum volume and volume at
pre-ejection; LASr, LAScd and LASct: LA reservoir, conduit and
contraction strain; ePLAGS: the echocardiographic pulmonary to LA global
strain ratio; DEI: LA storage function (diastolic ejection index); PEI:
LA channel function (passive ejection index); AEI: LA active systolic
function (active ejection index); LVEDI: index of the left ventricular
diameters at the end of diastole; LVEF: left ventricular ejection
fraction. |
LAVImax, LAVImin and LAVIpreA: The indices of left atrial
maximum volume, minimum volume and volume at pre-ejection; LASr, LAScd
and LASct: LA reservoir, conduit and contraction strain; ePLAGS: the
echocardiographic pulmonary to LA global strain ratio; DEI: LA storage
function (diastolic ejection index); PEI: LA channel function (passive
ejection index); AEI: LA active systolic function (active ejection
index); LVEDI: index of the left ventricular diameters at the end of
diastole; LVEF: left ventricular ejection fraction. |
LAVImax, LAVImin
and LAVIpreA: The indices of left atrial maximum volume, minimum volume
and volume at pre-ejection; LASr, LAScd and LASct: LA reservoir, conduit
and contraction strain; ePLAGS: the echocardiographic pulmonary to LA
global strain ratio; DEI: LA storage function (diastolic ejection
index); PEI: LA channel function (passive ejection index); AEI: LA
active systolic function (active ejection index); LVEDI: index of the
left ventricular diameters at the end of diastole; LVEF: left
ventricular ejection fraction. |
LAVImax, LAVImin and LAVIpreA: The
indices of left atrial maximum volume, minimum volume and volume at
pre-ejection; LASr, LAScd and LASct: LA reservoir, conduit and
contraction strain; ePLAGS: the echocardiographic pulmonary to LA global
strain ratio; DEI: LA storage function (diastolic ejection index); PEI:
LA channel function (passive ejection index); AEI: LA active systolic
function (active ejection index); LVEDI: index of the left ventricular
diameters at the end of diastole; LVEF: left ventricular ejection
fraction. |
LAVImax, LAVImin and LAVIpreA: The indices of left atrial
maximum volume, minimum volume and volume at pre-ejection; LASr, LAScd
and LASct: LA reservoir, conduit and contraction strain; ePLAGS: the
echocardiographic pulmonary to LA global strain ratio; DEI: LA storage
function (diastolic ejection index); PEI: LA channel function (passive
ejection index); AEI: LA active systolic function (active ejection
index); LVEDI: index of the left ventricular diameters at the end of
diastole; LVEF: left ventricular ejection fraction. |