Conventional tissue sealing agents, such as sutures or tissue adhesives, have been widely utilized in clinical settings to promote early formation and stability of blood clots. While these traditional techniques offer some advantages in clinical settings, their limitations have now been resolved by current bioadhesive technology. However, current bioadhesives have not been fully utilized and are often limited by weak bonding, poor mechanical interface compatibility, and burdensome application. In this study, I explored the potential of using interpenetrating alginate/polyacrylamide (PAAm) hydrogels as a smart material for bioadhesive patches in superficial wound healing. After mechanical testing, the PAAm material matched the biomechanical properties of human skin, and had comparable toughness to commercial bioadhesives. Furthermore, the PAAm dressing showed adequate release of hydration through an in vitro dehydration test. These findings suggest that PAAm-based therapies may be viable alternatives to conventional tissue sealing agents by providing efficient delivery of therapeutics and resolving challenges in interfacing and application on devices.