Mouse dry eye model
The mice were anesthetized and
the skin under the ear was disinfected with iodine. We use ophthalmic
scissors to make 5-7mm incisions under the ears. The exorbital lacrimal
gland was isolated gently and removed. The skin was sutured with 5–0
non-absorbable suture silk thread (ETHICON, China). The same procedure
was done to the Sham group without extraorbital lacrimal gland removal.