Supplementary Materials
Supplementary Figure 1 Differentially expressed gene (DEG)
selection and enrichment analysis. (A) DEG selection criteria and
details of up-regulated and down-regulated DEGs; (B) Logistics and
approach details in selecting target genes and pathways; (C) GO
enrichment analysis based on DEGs.
Supplementary Figure 2 Hug gene selection and biomarker
analysis. (A) Top 5 clusters of 334 DEGs after MCODE analysis in
Cytoscape; (B-C) Incorporating biomarker analysis in IPA and CytoHubba
hug gene selection showed ITGAM ranked the 1st at both
of mRNA and protein levels.