Biochemical measurements
We used fully clinical chemistry analyzer (Mindray BS-240) to test all the biochemical measurements as previously reported(Liu et al., 2021), including: serum uric acid (UA, μmol/L), serum creatinine (SCr, μmol/L), blood urea (mmol/L), alanine aminotransferase (ALT, U/L), aspartate aminotransferase (AST, U/L), total cholesterol (TC, mmol/L), serum triglycerides (TG, mmol/L), urine albumin (g/L), and urine creatinine (μmol/L).