CONCLUSION
As HIF-PHI is a kind of emerging drug for the treatment of renal anemia,
there is a lack of studies on its long-term efficacy and safety; for
example, its effect on kidney function and the progression of kidney
disease in patients remains unknown. Also, some studies have shown that
HIF-PHI can lower blood pressure and protect endothelial cells[43].
All these need to be further verified in more clinical human studies.