Reference
Arts, B., Jabben, N., Krabbendam, L., van Os, J., 2008. Meta-analyses of cognitive functioning in euthymic bipolar patients and their first-degree relatives. Psychol Med 38, 771-785.
Ayik, B., Kaya, H., Tasdelen, R., Sevimli, N., 2022. Retinal changes in bipolar disorder as an endophenotype candidate: Comparison of OCT-detected retinal changes in patients, siblings, and healthy controls. Psychiatry Res 313, 114606.
Balanza-Martinez, V., Rubio, C., Selva-Vera, G., Martinez-Aran, A., Sanchez-Moreno, J., Salazar-Fraile, J., Vieta, E., Tabares-Seisdedos, R., 2008. Neurocognitive endophenotypes (endophenocognitypes) from studies of relatives of bipolar disorder subjects: a systematic review. Neurosci Biobehav Rev 32, 1426-1438.
Bauer, I.E., Wu, M.J., Frazier, T.W., Mwangi, B., Spiker, D., Zunta-Soares, G.B., Soares, J.C., 2016. Neurocognitive functioning in individuals with bipolar disorder and their healthy siblings: A preliminary study. J Affect Disord 201, 51-56.
Bo, Q., Dong, F., Li, X., Li, F., Li, P., Yu, H., He, F., Zhang, G., Wang, Z., Ma, X., Wang, C., 2019. Comparison of cognitive performance in bipolar disorder, major depressive disorder, unaffected first-degree relatives, and healthy controls. Psychiatry Clin Neurosci 73, 70-76.
Bora, E., 2015. Neurodevelopmental origin of cognitive impairment in schizophrenia. Psychol Med 45, 1-9.
Bora, E., 2016. Differences in cognitive impairment between schizophrenia and bipolar disorder: Considering the role of heterogeneity. Psychiatry Clin Neurosci 70, 424-433.
Bora, E., Akgul, O., Ceylan, D., Ozerdem, A., 2018. Neurological soft signs in bipolar disorder in comparison to healthy controls and schizophrenia: A meta-analysis. Eur Neuropsychopharmacol 28, 1185-1193.
Bora, E., Ozerdem, A., 2017. Social cognition in first-degree relatives of patients with bipolar disorder: A meta-analysis. Eur Neuropsychopharmacol 27, 293-300.
Bora, E., Yucel, M., Pantelis, C., 2009. Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives. J Affect Disord 113, 1-20.
Breuer, R., Mattheisen, M., Frank, J., Krumm, B., Treutlein, J., Kassem, L., Strohmaier, J., Herms, S., Muhleisen, T.W., Degenhardt, F., Cichon, S., Nothen, M.M., Karypis, G., Kelsoe, J., Greenwood, T., Nievergelt, C., Shilling, P., Shekhtman, T., Edenberg, H., Craig, D., Szelinger, S., Nurnberger, J., Gershon, E., Alliey-Rodriguez, N., Zandi, P., Goes, F., Schork, N., Smith, E., Koller, D., Zhang, P., Badner, J., Berrettini, W., Bloss, C., Byerley, W., Coryell, W., Foroud, T., Guo, Y., Hipolito, M., Keating, B., Lawson, W., Liu, C., Mahon, P., McInnis, M., Murray, S., Nwulia, E., Potash, J., Rice, J., Scheftner, W., Zollner, S., McMahon, F.J., Rietschel, M., Schulze, T.G., 2018. Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics. Int J Bipolar Disord 6, 24.
Burdick, K.E., Goldberg, T.E., Cornblatt, B.A., Keefe, R.S., Gopin, C.B., Derosse, P., Braga, R.J., Malhotra, A.K., 2011. The MATRICS consensus cognitive battery in patients with bipolar I disorder. Neuropsychopharmacology 36, 1587-1592.
Calafiore, D., Rossell, S.L., Van Rheenen, T.E., 2018. Cognitive abilities in first-degree relatives of individuals with bipolar disorder. J Affect Disord 225, 147-152.
Cardenas, S.A., Kassem, L., Brotman, M.A., Leibenluft, E., McMahon, F.J., 2016. Neurocognitive functioning in euthymic patients with bipolar disorder and unaffected relatives: A review of the literature. Neurosci Biobehav Rev 69, 193-215.
Ceylan, D., Akdede, B.B., Bora, E., Aktener, A.Y., Hidiroglu Ongun, C., Tunca, Z., Alptekin, K., Ozerdem, A., 2020. Neurocognitive functioning during symptomatic states and remission in bipolar disorder and schizophrenia: A comparative study. Psychiatry Res 292, 113292.
Chen, E.Y., Shapleske, J., Luque, R., McKenna, P.J., Hodges, J.R., Calloway, S.P., Hymas, N.F., Dening, T.R., Berrios, G.E., 1995. The Cambridge Neurological Inventory: a clinical instrument for assessment of soft neurological signs in psychiatric patients. Psychiatry Res 56, 183-204.
Chrobak, A.A., Siuda-Krzywicka, K., Soltys, Z., Siwek, G.P., Bohaterewicz, B., Sobczak, A.M., Ceglarek, A., Tereszko, A., Starowicz-Filip, A., Fafrowicz, M., Marek, T., Siwek, M., Dudek, D., 2021. Relationship between neurological and cerebellar soft signs, and implicit motor learning in schizophrenia and bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry 111, 110137.
Ciufolini, S., Ponteduro, M.F., Reis-Marques, T., Taylor, H., Mondelli, V., Pariante, C.M., Bonaccorso, S., Chan, R., Simmons, A., David, A., Di Forti, M., Murray, R.M., Dazzan, P., 2018. Cortical thickness correlates of minor neurological signs in patients with first episode psychosis. Schizophr Res 200, 104-111.
Clark, L., Sarna, A., Goodwin, G.M., 2005. Impairment of executive function but not memory in first-degree relatives of patients with bipolar I disorder and in euthymic patients with unipolar depression. Am J Psychiatry 162, 1980-1982.
Correa-Ghisays, P., Balanza-Martinez, V., Selva-Vera, G., Vila-Frances, J., Soria-Olivas, E., Vivas-Lalinde, J., San Martin, C., Borras, A.M., Ayesa-Arriola, R., Sanchez-Moreno, J., Sanchez-Ort, J., Crespo-Facorro, B., Vieta, E., Tabares-Seisdedos, R., 2017. Manual motor speed dysfunction as a neurocognitive endophenotype in euthymic bipolar disorder patients and their healthy relatives. Evidence from a 5-year follow-up study. J Affect Disord 215, 156-162.
Correll, C.U., Penzner, J.B., Lencz, T., Auther, A., Smith, C.W., Malhotra, A.K., Kane, J.M., Cornblatt, B.A., 2007. Early identification and high-risk strategies for bipolar disorder. Bipolar Disord 9, 324-338.
Daban, C., Mathieu, F., Raust, A., Cochet, B., Scott, J., Etain, B., Leboyer, M., Bellivier, F., 2012. Is processing speed a valid cognitive endophenotype for bipolar disorder? J Affect Disord 139, 98-101.
Douglas, K.M., Gallagher, P., Robinson, L.J., Carter, J.D., McIntosh, V.V., Frampton, C.M., Watson, S., Young, A.H., Ferrier, I.N., Porter, R.J., 2018. Prevalence of cognitive impairment in major depression and bipolar disorder. Bipolar Disord 20, 260-274.
Feng Y,Hu X,Tian Y,Jiang Y,Wang Z,Gao Z,Bao L., 2017. Comparative study of neurological soft signs in remittent schizophrenia and non-psychotic first-degree relatives. Chinese Journal of Nervous and Mental Diseases 43, 85-88.
Feng, Y., Wang, Z., Lin, G., Qian, H., Gao, Z., Wang, X., Li, M., Hu, X., Li, Y., 2020. Neurological soft signs and neurocognitive deficits in remitted patients with schizophrenia, their first-degree unaffected relatives, and healthy controls. Eur Arch Psychiatry Clin Neurosci 270, 383-391.
Gotra, M.Y., Hill, S.K., Gershon, E.S., Tamminga, C.A., Ivleva, E.I., Pearlson, G.D., Keshavan, M.S., Clementz, B.A., McDowell, J.E., Buckley, P.F., Sweeney, J.A., Keedy, S.K., 2020. Distinguishing patterns of impairment on inhibitory control and general cognitive ability among bipolar with and without psychosis, schizophrenia, and schizoaffective disorder. Schizophr Res 223, 148-157.
Gottesman, II, Gould, T.D., 2003. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 160, 636-645.
Hamilton, M., 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry 23, 56-62.
Hellhammer, D., Meinlschmidt, G., Pruessner, J.C., 2018. Conceptual endophenotypes: A strategy to advance the impact of psychoneuroendocrinology in precision medicine. Psychoneuroendocrinology 89, 147-160.
Hu, B., Cha, J., Fullerton, J.M., Hesam-Shariati, S., Nakamura, K., Nurnberger, J.I., Anand, A., 2022. Genetic and environment effects on structural neuroimaging endophenotype for bipolar disorder: a novel molecular approach. Transl Psychiatry 12, 137.
Hu, R., Stavish, C., Leibenluft, E., Linke, J.O., 2020. White Matter Microstructure in Individuals With and At Risk for Bipolar Disorder: Evidence for an Endophenotype From a Voxel-Based Meta-analysis. Biol Psychiatry Cogn Neurosci Neuroimaging 5, 1104-1113.
Iacono, W.G., 2018. Endophenotypes in psychiatric disease: prospects and challenges. Genome Med 10, 11.
Jiang, B., Kenna, H.A., Rasgon, N.L., 2009. Genetic overlap between polycystic ovary syndrome and bipolar disorder: the endophenotype hypothesis. Med Hypotheses 73, 996-1004.
Jiang, X., Mio, M., Dimick, M.K., Zou, Y., Sultan, A.A., Goldstein, B.I., 2022. Association of Lithium and Second-Generation Antipsychotics with Neurocognition in Youth with Bipolar Disorder. J Child Adolesc Psychopharmacol 32, 61-69.
Kessing, L.V., Andersen, P.K., 2017. Evidence for clinical progression of unipolar and bipolar disorders. Acta Psychiatr Scand 135, 51-64.
Kieseppa, T., Tuulio-Henriksson, A., Haukka, J., Van Erp, T., Glahn, D., Cannon, T.D., Partonen, T., Kaprio, J., Lonnqvist, J., 2005. Memory and verbal learning functions in twins with bipolar-I disorder, and the role of information-processing speed. Psychol Med 35, 205-215.
Kjaerstad, H.L., Mistarz, N., Coello, K., Stanislaus, S., Melbye, S.A., Harmer, C.J., Vinberg, M., Miskowiak, K., Kessing, L.V., 2020. Aberrant cognition in newly diagnosed patients with bipolar disorder and their unaffected relatives. Psychol Med 50, 1808-1819.
Kulkarni, S., Jain, S., Janardhan Reddy, Y.C., Kumar, K.J., Kandavel, T., 2010. Impairment of verbal learning and memory and executive function in unaffected siblings of probands with bipolar disorder. Bipolar Disord 12, 647-656.
Lenzenweger, M.F., 2013. Thinking clearly about the endophenotype-intermediate phenotype-biomarker distinctions in developmental psychopathology research. Dev Psychopathol 25, 1347-1357.
Luperdi, S.C., Correa-Ghisays, P., Vila-Frances, J., Selva-Vera, G., Salazar-Fraile, J., Cardoner, N., Ruiz-Veguilla, M., Livianos, L., Tabares-Seisdedos, R., Balanza-Martinez, V., 2021. Is processing speed a valid neurocognitive endophenotype in bipolar disorder? Evidence from a longitudinal, family study. J Psychiatr Res 141, 241-247.
McGue, M., 2017. Irving Gottesman and the concept of endophenotype. Am J Med Genet C Semin Med Genet 175, 341-342.
Mrad, A., Wassim Krir, M., Ajmi, I., Gaha, L., Mechri, A., 2016. Neurological soft signs in euthymic bipolar I patients: A comparative study with healthy siblings and controls. Psychiatry Res 236, 173-178.
Nasab, A.F., Abrishami, B.S., Ghavami, B., Hosseini-Zijoud, S.M., 2017. Comparison of Neurological Soft Signs between Psychotic and Non Psychotic Patients. J Clin Diagn Res 11, VC09-VC11.
Normala, I., Abdul, H.A., Azlin, B., Nik Ruzyanei, N.J., Hazli, Z., Shah, S.A., 2010. Executive function and attention span in euthymic patients with bipolar 1 disorder. Med J Malaysia 65, 199-203.
YANG Chao.FU Yuewen.ZHANG Li.WANG Yan.YANG Ping., 2018. Bioinformatics Analysis of Genes Related to Bipolar Disorder in Children and Adolescents. Chinese General Practice 21, 4098-4103.
Pitzianti, M., Casarelli, L., Pontillo, M., Vicari, S., Armando, M., Pasini, A., 2019. Antipsychotics Do Not Influence Neurological Soft Signs in Children and Adolescents at Ultra-High Risk for Psychosis: A Pilot Study. J Psychiatr Pract 25, 186-191.
Rabelo-da-Ponte, F.D., Feiten, J.G., Mwangi, B., Barros, F.C., Wehrmeister, F.C., Menezes, A.M., Kapczinski, F., Passos, I.C., Kunz, M., 2020. Early identification of bipolar disorder among young adults - a 22-year community birth cohort. Acta Psychiatr Scand 142, 476-485.
Rathod, B., Kaur, A., Basavanagowda, D.M., Mohan, D., Mishra, N., Fuad, S., Nosher, S., Alrashid, Z.A., Heindl, S.E., 2020. Neurological Soft Signs and Brain Abnormalities in Schizophrenia: A Literature Review. Cureus 12, e11050.
Rodriguez, L., de la Vega, I., Torrijos, S., Barabash, A., Ancin, I., Pelaez, J.C., Lopez-Ibor, J.J., Cabranes, J.A., 2012. A study of verbal memory in a sample of euthymic patients with bipolar disorder. Actas Esp Psiquiatr 40, 257-265.
Sagheer, T.A., Assaad, S., Haddad, G., Hachem, D., Haddad, C., Hallit, S., 2018. Neurological soft signs in bipolar and unipolar disorder: A case-control study. Psychiatry Res 261, 253-258.
Sandstrom, A., Sahiti, Q., Pavlova, B., Uher, R., 2019. Offspring of parents with schizophrenia, bipolar disorder, and depression: a review of familial high-risk and molecular genetics studies. Psychiatr Genet 29, 160-169.
Segar, R., Chhabra, H., Sreeraj, V.S., Parlikar, R., Kumar, V., Ganesan, V., Kesavan, M., 2021. fNIRS study of prefrontal activation during emotion recognition-A Potential endophenotype for bipolar I disorder? J Affect Disord 282, 869-875.
Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E., Hergueta, T., Baker, R., Dunbar, G.C., 1998. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59 Suppl 20, 22-33;quiz 34-57.
Shi, C., Kang, L., Yao, S., Ma, Y., Li, T., Liang, Y., Cheng, Z., Xu, Y., Shi, J., Xu, X., Zhang, C., Franklin, D.R., Heaton, R.K., Jin, H., Yu, X., 2015. The MATRICS Consensus Cognitive Battery (MCCB): Co-norming and standardization in China. Schizophr Res 169, 109-115.
Simpson, G.M., Angus, J.W., 1970. A rating scale for extrapyramidal side effects. Acta Psychiatr Scand Suppl 212, 11-19.
Turetsky, B.I., Calkins, M.E., Light, G.A., Olincy, A., Radant, A.D., Swerdlow, N.R., 2007. Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures. Schizophr Bull 33, 69-94.
Van Rheenen, T.E., Lewandowski, K.E., Tan, E.J., Ospina, L.H., Ongur, D., Neill, E., Gurvich, C., Pantelis, C., Malhotra, A.K., Rossell, S.L., Burdick, K.E., 2017. Characterizing cognitive heterogeneity on the schizophrenia-bipolar disorder spectrum. Psychol Med 47, 1848-1864.
Van Rheenen, T.E., Meyer, D., Rossell, S.L., 2014. Pathways between neurocognition, social cognition and emotion regulation in bipolar disorder. Acta Psychiatr Scand 130, 397-405.
Young, R.C., Biggs, J.T., Ziegler, V.E., Meyer, D.A., 1978. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 133, 429-435.