Results
During the study period, there were 1759 drugs registered by the EMA.
Among them, 1409 were authorized products. In total, 4215 documents
incorporating product information, public assessment report, and
scientific discussion documents were extracted from the authorized
products. A list of keywords on adaptive designs (Table 2) was used to
identify 91 documents of interest after 4 duplicated documents were
removed [5, 7-10].
Table 2. Definitions of adaptive designs