CD40-CD40L and ICOS-ICOSL expression are correlated in nasal
polyps of CRS patients
Then, we investigated the correlation of CD40-CD40L and ICOS-ICOSL
expression in the nasal tissue of our CRS patients. Our correlation
analysis results show that there was a significantly positive
correlation between ICOS and CD40 expression (r=0.7875,
p<0.0001, Fig. 2A), ICOSL and CD40 expression (r=0.5232,
p=0.0061, Fig. 2B), ICOS and CD40L expression (r=0.5604, p=0.0102, Fig.
2D), as well as ICOS and ICOSL expression (r=0.6389, p=0.0018, Fig. 2F).
Similar correlation tendencies were observed between CD40L and CD40
expression (Fig. 2C), as well as CD40L and ICOSL expression (Fig. 2E),
whereas there was no significant correlation shown.