Rg1 reduced oxidative stress in NSCs by increasing antioxidant capacity
In order to study whether Rg1 could delayed the aging of NSCs by reducing oxidative damage, we measured the indicators related to oxidative stress.In comparison to the Control group, the D-gal group had lower SOD (Fig.3 A) and CAT (Fig.3 B) activities, but elevated MDA (Fig.3 C), 4-HNE (Fig.3 D), and 8-OHdG (Fig.3 E) contents. In comparison to the D-gal group, the D-gal +Rg1 group had higher SOD and CAT activity, but lower MDA, 4-HNE, and 8-OHdG contents(paired t test,n=4-6,p<0.05). The results showed that Rg1 delayed the aging of NSCs by reducing oxidative damage.