Keywords: Kids, COVID-19, ACE2, Immunity, Cytokine Storm

Key Message

This article review may provide convincing answers to the questions raised by many pediatricians and infants’ parents about the consequences of infection on children and steps to be taken if their child has symptoms of, or tests positive for, COVID-19. The kid’s immune response against SARS‑ CoV-2 infection is early initiative with low immunological tone to prevent overactive immunity and lung damage. More studies are needed to explain why COVID-19 seems to affect children less than adults since it is unlikely that there is a single explanation for why COVID-19 seems to affect children less than adults.