Oceanic transform faults are intriguing in that they do not produce earthquakes as large as might be expected given their dimensions. We use 1-year of local seismicity recorded on an array of ocean bottom seismometers (OBS) and geophysical data to study the seismotectonic properties of the Chain transform, located in the equatorial Mid-Atlantic. We extend our analysis back in time by considering stronger earthquakes (M_W ≥ 5.0) from global catalogs. We divide Chain into three areas (eastern, central, and western) based on multi-dimensional OBS seismicity cluster analysis. Seismic activity recorded by the OBS is the highest at the eastern area of Chain where there is a lozenge shaped topographic high, a negative rMBA gravity anomaly, and only a few historical M_W ≥ 5.5 events. OBS seismicity rates are lower in the western and central areas. However, these areas accommodate the majority of seismic moment release, as inferred from both OBS and historical data. We find no evidence of remote dynamic triggering and only weak evidence of tidal and static stress triggering. Higher b-values are significantly correlated with lower rMBA and also with shallower bathymetry, potentially related to thickened crust. Our results suggest high lateral heterogeneity along Chain: Patches with moderate to low OBS seismicity rates that occasionally host M_W ≥ 6.0 earthquakes are interrupted by segments with abundant OBS activity but few historical events with 5.5 ≤ M_W < 6.0. This segmentation is possibly due to variable fluid circulation and alteration, which may also be variable in time.