Dietary Remediation
The humoral immune response in the gastrointestinal tract is mediated by IgA+ memory B cells and IgA-producing plasma cells (activated B cells) in the gut-associated lymphoid tissue (GALT). Commensal and symbiotic bacteria act as critical B cell stimuli, playing an important role for the maturation of the GALT and further induce IgA production by B cells. The interrelation of dietary components, microbiome and B cell function are critical to the production of (auto)antibodies (Petta et al, 2018). Therefore, diet is critical to controlling autoantibody production, in turn, controlling the symptoms of autoimmune disease.