Data collection and statistical analysis
Data on characteristics, including sex, age, smoking status, alcohol
consumption, comorbidities, the results of acid-fast bacilli (AFB) smear
and mycobacterial culture, laboratory results, anti-TB regimen, anti-TB
drug related side effects, and the onset and management of AKI, were
collected. The estimated glomerular filtration rate (eGFR) was
calculated using the Modification of Diet in Renal Disease formula
[19].
All data are expressed as the number (%), mean ± standard deviation, or
median (interquartile range). Intergroup differences were determined
using a t test or Mann–Whitney U test for continuous
variables based on their normality, and the chi-square test or Fisher’s
exact test was used for categorical variables, as appropriate. Time to
AKI for each variable was compared using the Kaplan–Meier method with
the log-rank test. All variables with a p value ≤0.1 in
univariate analysis were subjected to a multivariate Cox proportional
hazards regression analysis to compute the adjusted hazard ratios (HRs)
and 95% confidence intervals (CIs). All analyses were conducted using
the Statistical Package for the Social Sciences 24.0 ([SPSS]; SPSS
Inc, Chicago, IL, USA). Statistical significance was set at p< 0.05.