Trends of incidence, mortality and DALYs of gynecological malignancies from 1990 2019
From 1990 to 2019, the numbers of incidence cases, deaths and DALYs of cervical cancer, uterine cancer and ovarian cancer all significantly increased. The EAPCs in ASIR of three cancers from 1990 to 2019 were 1.61 (95% CI: 1.35, 1.88), 1.26 (95% CI: 0.58, 1.94) and 1.88 (95% CI: 1.79, 1.98), respectively. The EAPC of ASMR and ASDR among patients with cervical cancer in 20 years was not much different with 0.09 (95% CI: -0.18, 0.36) and 0.16 (95%: -0.09, 0.41), respectively. Overall downward trends in ASMR and ASDR among patients with uterine cancer were observed with the EAPC of -2.27 (95% CI: -2.88, -1.66) and -2.21 (95%CI: -2.81, -1.60). The EAPC of death and DALYs of ovarian cancer still showed an upward trend with 1.51 (95% CI: 1.42, 1.61) and 1.15 (95%CI: 1.04, 1.25) (Table 1, Figure 2).
The incidence rate of cervical cancer aged 35-70 years was increasing from 1990 to 2019. In recent years, the incidence rate of uterine cancer has declined in most age-specific groups, but had shown a youth-oriented tendency. The incidence and death rate of ovarian cancer showed an upward trend in overall groups. Overall downward trends in mortality and DALYs rates were observed in cervical cancer and uterine cancer at most age-specific groups from 1999 to 2019. The DALYs rates of ovarian cancer increased in most age-specific groups (Figure 2).