Evaluation of burden of gynecological malignancies
The incidence and mortality of gynecological malignancies in the GBD
dataset were evaluated in the following ways: (1) based on all the data
sources that reported incidence and mortality of cervical cancer,
uterine cancer and ovarian cancer (with international disease
classification codes), the mortality-to-incidence ratio (MIR) was
computed; (2) we calculated mortality estimates by multiplying cancer
register incidence data by the MIR; (3) all these data were used as
input to follow the Cause of Death Ensemble model process to determine
the cancer-specific mortality of cervical cancer, uterine cancer and
ovarian cancer; and (4) we divided the cancer-specific mortality of
cervical cancer, uterine cancer and ovarian cancer estimates by the MIR
to generate incidence. DALYs were computed by adding years of life lost
(YLLs) and years lived with disability (YLDs).