Figure-2: Preclinical Cancer models
In vitro models for angiogenesis research
Since angiogenesis is involved in embryonic development, reproductive function, adult wound healing, and a variety of diseases, including cancer, it has attracted the attention of researchers. Angiogenesis is defined as the production of new capillaries from pre-existing vessels. In this article, we discuss and highlight a few of the most common and current in vitro models for angiogenesis research, including 2D models and 3D spherical and plate-shaped models, particularly (Folkman, 2007).