Introduction
The detection and assessment of areas of leakage in fluorescence angiography (FA) images are crucial for both the diagnosis and management of different choroidal and retinal diseases. Leaking fluorescein may result from attenuated blood vessels such as retinal neovascularization (NVE), choroidal neovascularization (CNV), or through a weakened retinal pigment epithelium (RPE) that no longer prevents leakage of fluorescein from the choroid. (1) FFA leakage is characterized by early hyperfluorescence, increasing with time in both area and intensity, and blurring of the vessel’s margins. (1) It occurs as a result of two main mechanisms: dysfunction of existing vascular endothelial tight junctions as seen in diabetic retinopathy (DR), cystoid macular edema (CME), branch and central retinal vein occlusion or due to the primary absence of vascular endothelial tight junctions which seen in CNVs, some vascular disorders like Coats disease, or Behcet׳s disease. (2,3) We reported fluorescence leakage secondary to rhegmatogenous retinal detachment (RD) in a seven-year-old child and explained how this association made confusion to reach the diagnosis.