Abstract
Human health is burdened by a diverse range of diseases, particularly
chronic diseases. Free radicals and other oxidants are implicated in the
development of those diseases as free radicals induced oxidative stress.
Antioxidants are salient substances that involve maintaining a normal
long life by scavenging the free radicals in the body. Phycocyanin is
free radicals’ scavenger with the ability to find and tackle the side
effects of free radicals; phycocyanin also possesses other physiological
and pharmaceutical properties.
This research aimed at evaluating the effectiveness of
TiO2 nanoparticles, and reduced graphene oxide titanium
dioxide nanoparticles (hereinafter referred to rGO-TiO2nanoparticles) under visible light conditions to boost the accumulation
of phycocyanin in Arthrospira (Spirulina) platensis(FACHB-314 ) cells. The experimental results indicated that both
nanoparticles exhibited high phycocyanin content accumulation compared
to the control group. Under optimized visible light conditions of 165
μmol/m2/s wavelength and continuous lighting with
white lights, the phycocyanin content of 80.3 mg/g and maximum yield of
phycocyanin production was 97.16 mg/L in the rGO-TiO2nanoparticles culture; 55.7 mg/g and 81.88 mg/L in the
TiO2 nanoparticles culture, compared to 75.5 mg/g and
81.86 in the control culture. The maximum dry-weight biomass cells were
observed under the control group compared to the experimental
conditions. These research results indicate that
rGO-TiO2 nanoparticles have potential commercial
applications due to their excellent properties, and can be used inA. platensis and other microalgae cultivation to optimize
productivity.
Keywords: rGO-TiO2, FACHB-314 ,
phycocyanin, nanoparticles, algae