Methods
114 confirmed cases of sickle cell disease attended special clinical
camps. Patients of all age group were invited to attend. Their complete
documented and undocumented medical history, available relevant medical
information, original Hb analysis reports, were assessed using a
questionnaire. Patients were clinically examined, present symptoms,
major medical illness, history of pain episodes, transfusions were
recorded. History of usage of HU was specifically elucidated. Hemoglobin
electrophoresis/High performance liquid chromatography reports from the
date of diagnosis (pre-hydroxyurea)were reviewed to study percentage of
HbS and HbF. During this camp,89 patients underwent a point of care Hb
electrophoresis test (post-hydroxyurea)(Using microchip-based cellulose
acetate electrophoresis test) to study present day HbS and HbF levels.
Average of Hb S and Hb F levels on the date of diagnosis and present day
were calculated and statistically analyzed for significance.