Methods
114 confirmed cases of sickle cell disease attended special clinical camps. Patients of all age group were invited to attend. Their complete documented and undocumented medical history, available relevant medical information, original Hb analysis reports, were assessed using a questionnaire. Patients were clinically examined, present symptoms, major medical illness, history of pain episodes, transfusions were recorded. History of usage of HU was specifically elucidated. Hemoglobin electrophoresis/High performance liquid chromatography reports from the date of diagnosis (pre-hydroxyurea)were reviewed to study percentage of HbS and HbF. During this camp,89 patients underwent a point of care Hb electrophoresis test (post-hydroxyurea)(Using  microchip-based cellulose acetate electrophoresis test) to study present day HbS and HbF levels. Average of Hb S and Hb F levels on the date of diagnosis and present day were calculated and statistically analyzed for significance.