Scope of Review: Auditory and Visual, Sensory andWorking Memory
Perturbed bottom-up functioning impairs upstream cognition (Javitt, 2009; Javitt & Sweet, 2015). If sensory encoding is impaired then the information derived from the impoverished signal will produce further problems. An immediate consequence of impaired SM is reduced information available for WM. In addition, WM deficits in schizophrenia could negatively impact SM too: If WM is inefficient, then manipulating incoming sensory information will also be impaired. Improvements anywhere along this loop could have cascading consequences (Figure 1). A first step is to characterize the relationships between SM and WM biomarkers and how they are impacted along SSD.