Introduction:
Primary colorectal lymphoma (PRL) accounts for 1.4% of all cases of non-Hodgkin’s lymphoma (NHL) and less than 1% of all colorectal malignancies. Although the gastrointestinal (GI) tract is the most common site of extranodal lymphoma, colorectal lymphoma is rare [1]. Dawson and al established criteria for the diagnosis of PRL in 1961 including the absence of clinically enlarged lymphadenopathy in physical examination, the absence of enlarged mediastinal lymph nodes on chest x-ray, normal white blood cell count and bone marrow biopsy, and the absence of abnormalities of the liver and spleen [2]. While treatment strategies in nodal NHL are well established, management of PRL is still unclear [3].  We present the case of a 38-year-old woman, diagnosed with a stage IIE PRL