Introduction:
COVID-19 was considered a devastating worldwide pandemic after it caused the deaths of millions of people worldwide(1). Many types of research have studied the effects of COVID-19 on physical and mental health during pregnancy(2–4). Compared to nonpregnant women of the same reproductive age, pregnant women are at higher risk of severe illness and mortality from COVID-19, besides also being at increased risk of unfavorable pregnancy outcomes such as preterm birth(5–7). At the onset of vaccination during this pandemic, there was a paucity of safety data on COVID-19 immunization in pregnant women. However, later, the available evidence documented no harmful maternal or neonatal consequences of the administration of COVID-19 vaccines to pregnant women, and there is also a growing body of evidence that supports the safety of such vaccination(8–12). Findings from three safety monitoring systems revealed no safety concerns for pregnant women who received an mRNA COVID-19 vaccine in their late pregnancy, or for newborns(13). The acceptance among pregnant women varies, even with the increasing evidence. However, the immunization rate is still low among pregnant women(14). Pfizer and Moderna vaccines are the preferred vaccines for eligible pregnant women of any age because of their more extensive experience of their use in pregnancy(15). Therefore, this study was conducted to investigate the effect of different COVID-19 vaccines approved in saudia arabia on perinatal outcomes.