Patients
Between August 2016 and June 2023, 85 children diagnosed with AA who underwent allogeneic HSCT were included in this study. The patients were treated at the pediatric stem cell transplantation unit of Wuhan Children’s Hospital. ABO compatibility was documented in 38 donor–recipient pairs, while ABO incompatibility was documented in 47 pairs (17 major, 21 minor, 9 bi-directional).
The protocol of this clinical observation study adhered to the tenets of the Declaration of Helsinki and received approval from the Wuhan Children’s Hospital Ethics Committee (approval no. 2022R071-E01). Written informed consent was obtained from all patients in accordance with the principles of the Declaration of Helsinki.