Materials and Methods
Patient
selection
We identified a total of 119 histopathologically-proven SCNEC cases from
Sun Yat-sen University Cancer Center (SYSUCC), diagnosed between January
2010 and December 2018. Eligibility criteria included (1) biopsy-proven
SCNEC; (2) age >18 years; and (3) chemotherapy plus radical
hysterectomy/chemoradiotherapy. Exclusion criteria included disseminated
disease, history of previous or synchronous malignant tumors, pregnancy
or lactation, and insufficient data. A total of 103 patients met the
inclusion criteria and were considered eligible for the study
(Figure 1 ). The institutional ethical review board of SYSUCC
approved this retrospective analysis of anonymous data. Requirement for
informed consent was waived by the ethical review boards (No.:
B2020-231-01).