Maternal characteristics and renal function between singleton and twin pregnancies
Maternal characteristics are shown in Table 1. In this study, maternal age, pre-pregnancy body mass index, and nulliparity rate were not significantly different between singleton and twin pregnancies. However, the rate of fetal growth restriction was significantly higher in twin pregnancies than that in singleton pregnancies (p < 0.001). A comparison of maternal renal function between singleton and twin pregnancies is presented in Table 2. The gestational age at blood test were significantly earlier in twin pregnancies than that in singleton pregnancies (p < 0.001). Serum creatinine level was significantly higher and eGFR was significantly lower in twin pregnancies than that in singleton pregnancies (p < 0.001). In addition, the rate of renal dysfunction was significantly higher in twin than that in singleton pregnancies (7.9% vs. 2.6%; p < 0.001).