3.1 The reaction pathway of MNTzA
In Figure 1, the C on the alkenyl group of FOX-7 is gradually approached
by the N on the amino group of CH3NHNH2,
and the N atom on the amino group of FOX-7 is gradually approached by
the H atom on the amino group, resulting in a synergistic reaction and
generating intermediate IM1. The NH3 connected to IM1 is
very unstable and breakage of C-N bond is carried out immediately,
generating a stable intermediate IM2 with relatively low energy.