3.1 The reaction pathway of MNTzA
In Figure 1, the C on the alkenyl group of FOX-7 is gradually approached by the N on the amino group of CH3NHNH2, and the N atom on the amino group of FOX-7 is gradually approached by the H atom on the amino group, resulting in a synergistic reaction and generating intermediate IM1. The NH3 connected to IM1 is very unstable and breakage of C-N bond is carried out immediately, generating a stable intermediate IM2 with relatively low energy.