Figure Legends
FIGURE 1 A 6-month-old boy received pLT for biliary atresia.18F-FDG PET/CT was performed 2 years and 6 months
after the operation due to long-term fever and lymphadenopathy. Key
findings of the 18F-FDG PET/CT scan report include the
following. First, there were multiple enlarged lymph nodes in the
cervical, bilateral parapharyngeal space and right supraclavicular
fossa, with abnormally high metabolism, and PTLD was considered. Second,
the wall of the nasopharynx was diffusely thickened and the metabolism
was abnormally increased; additionally, the morphology of the bilateral
tonsils is plump, and the metabolism is diffusely and abnormally high;
so, inflammation was considered in our conclusion. (A and B)
Maximum-intensity projection and fusion of 18F-FDG
PET/CT at the lymph node biopsy site. (C) Axial fusion18F-FDG PET/CT imaging revealed high uptake in the
right cervical lymph node. (D) During diagnostic CT imaging, a spherical
mass was seen in the right side of the neck. (E) Hematoxylin and eosin
staining (×100 magnification) showed lymphoid infiltration. (F)
EBV-encoding region in situ hybridization (×200 magnification) showed a
positive result.
FIGURE 2 ROC curve. The AUC of the ROC curve was 0.923 (95%
confidence interval, 0.834–1.000). The cut-off value at the maximum
value of Youden’s index was 0.264, and the sensitivity and specificity
were 93.6% and 94.7%, respectively.
FIGURE 3 False-positive and false-negative cases. (A–F)
False-positive case. A 7-month-old boy received pLT for biliary atresia.18F-FDG PET/CT imaging was performed 8 months after
the operation due to lymphadenopathy. Key findings of the18F-FDG PET/CT scan report include the following.
First, the top and posterior walls of the nasopharynx were thickened,
and the metabolism was abnormally increased. Second, there were multiple
cervical enlarged lymph nodes and abnormal metabolism; the above
considerations are consistent with PTLD. (A and B) Maximum-intensity
projection and fusion of 18F-FDG PET/CT at the lymph
node biopsy site. (C) Axial fusion 18F-FDG PET/CT
imaging showed high uptake in the right cervical lymph node. (D) During
diagnostic CT imaging, a spherical mass was seen in the right side of
the neck. (E) Hematoxylin and eosin staining (×100 magnification) showed
lymphoid infiltration. (F) EBV-encoding region in situ hybridization
(×200 magnification) showed a negative result. (G–L) False-negative
case. A 5-month-old boy received pLT for biliary atresia.18F-FDG PET/CT imaging was performed 8 months after
the operation due to long-term fever and lymphadenopathy. Key findings
of the 18F-FDG PET/CT scan report include the
following. First, there were multiple enlarged lymph nodes in the
cervical, mediastinum (anterior trachea), bilateral axial,
retroperitoneal autonomous aorta and bilateral inguinal areas, with
increased metabolism to varying degrees. Second, the wall of the
nasopharynx was significantly thickened, and the metabolism was
abnormally increased. Third, the soft tissue nodule under the right
diaphragm in the abdominal cavity exhibited an abnormally increased
metabolism; these findings were consistent with PTLD. (G and H)
Maximum-intensity projection and fusion of 18F-FDG
PET/CT at the lymph node biopsy site. (I) Axial fusion18F-FDG PET/CT imaging showed high uptake in the
inguinal lymph node. (J) During diagnostic CT imaging, a spherical mass
could be seen in the groin. (K) Hematoxylin and eosin staining (×100
magnification) showed lymphoid infiltration. (L) EBV-encoding region in
situ hybridization (×200 magnification) showed a positive result.