Results

In this study, 64 patients with influenza were included. The average age of the patients was 57.50 years, and the average hospitalization time was 7.50 days. Twenty-eight patients (43.8%) were male, and approximately 81% had a medical record of a pre-existing medical condition (Table 1).
The most common pre-existing diseases amongst the patients were high blood pressure (26 patients, 17.8%), heart diseases (20 patients, 13.7%), and diabetes mellitus (16 patients, 11%), respectively.
Fourteen people (21.9%) had no risk factors for severe disease. The most common risk factors were chronic pulmonary diseases (including asthma), cardiovascular disease, kidney disease, liver disease, and hematologic and metabolic disorders (including diabetes) (Table 3).
The most common treatment regimens for patients with influenza were oseltamivir (51 patients, 14.8%), vancomycin (45 patients, 13.1%), levofloxacin (42 patients, 12.2%), and corticosteroids (26 patients, 7.6%). More than 41% of patients reported a history of prednisolone use.
The most common symptoms of the disease in people with influenza were cough (51 patients, 13.4%), fever (50 patients, 13.2%), myalgia (41 patients, 10.8%), sputum (37 patients, 9.7%), chills (35 patients, 9.2%), and shortness of breath (32 patients, 8.4%,).
Lung involvement was not reported in 5 patients (7.8%); these patients had been admitted to the emergency department and were discharged from the hospital after receiving initial treatment with normal CT scan findings.
Regarding the outcomes of the disease, 58 patients (90.6%) survived, and 6 patients (9.4%) passed away. The relationship between the symptoms and the disease outcome was not significant. (P=0.277). However, the relationship between oxygen saturation (P=0.037), pulse rate (P=0.012), and respiratory rate (P<0.0001) and the outcomes was significant. The relationship between the risk factors for contracting influenza and the outcome was not significant (P=0.931). However, the relationship between the outcome and ALP (P=0.001) and ALT (P=0.003) in patients with influenza infection was significant. The relationship between imaging records and the outcomes was not significant (P>0.05) (Table 2)
The results of the univariate and multivariate logistic regression investigations showed that among all studied vital signs, clinical signs, laboratory and imaging findings, oxygen saturation percentage, pulse rate, respiratory rate, ALP, and ALT had significant relationships with the outcomes of the disease. In the univariate regression model, parameters of oxygen saturation (ORR=0.821, P=0.007), respiration rate (ORR=1.298, P=0.003), and ALP (ORR=1.12, P=0.022) had significant relationships with the outcome.