Table 2: The mean score, medians, and frequency response of each item of the LAEP (n= 309)
Symptoms LAEP items Median (range) Never a problem (1) Rarely a problem (2) Sometimes a problem (3) Always or often a problem (4) Mean ±SD
Mood and behavior (Psychiatric symptoms) Depression 1 (1-4) 176 (56.96%) 69 (22.33%) 53 (17.15%) 11 (3.56%) 1.67 ± 0.88
Restlessness 1 (1-4) 174 (56.3%) 116 (37.5%) 19 (6.14%) 0 (0%) 1.50 ± 0.61
Feelings of anger & aggression to others 3 (1-4) 22 (7.12%) 107 (34.63%) 135 (43.7%) 45 (14.6%) 2.66 ± 0.81
Nervousness or agitation 2 (1-4) 75 (24.3%) 155 (50.2%) 71 (22.97%) 8 (2.6%) 2.04 ± 0.76
Cosmetic
(Non-CNS symptoms) Hair loss 1 (1-4) 175 (56.6%) 90 (29.1%) 37 (11.97%) 7 (2.3%) 1.60 ± 0.79
Problems with Skin (e.g. achne or rash) 1 (1-4) 288 (93.2%) 15 (4.85%) 5 (1.62%) 1 (0.32%) 1.09 ± 0.37
Gastrointestinal
(Non-CNS symptoms) Upset stomach 1 (1-4) 264 (85.4%) 35 (11.32%) 10 (3.24%) 0 (0%) 1.18 ± 0.46
Weight gain 1 (1-4) 273 (88.35%) 33 (10.68%) 3 (0.97%) 0 (0%) 1.13 ± 0.36
Trouble with mouth or gums 1 (1-4) 300 (97.1%) 7 (2.26%) 2 (0.65%) 0 (0%) 1.04 ± 0.22
Neurological
(CNS related symptoms) Difficulty in concentrating 1 (1-4) 241 (77.99%) 53 (17.15%) 15 (4.85%) 0 (0%) 1.27 ± 0.54
Double or blurred vision 1 (1-4) 277 (89.6%) 25 (8.1%) 5 (1.62%) 2 (0.65%) 1.13 ± 0.43
Headache 2 (1-4) 140 (45.3%) 131 (42.4%) 37 (11.97%) 1 (0.32%) 1.67 ± 0.69
Shaky hands 1 (1-4) 222 (71.84%) 51 (16.5%) 32 (10.36%) 4 (1.29%) 1.41 ± 0.73
Unsteadiness 1 (1-4) 286 (92.6%) 22 (7.11%) 1 (0.32%) 0 (0%) 1.08 ± 0.28
Tiredness 2 (1-4) 116 (37.5%) 157 (50.8%) 34 (11%) 2 (0.65%) 1.75 ± 0.67
Dizziness 1 (1-4) 273 (88.35%) 33 (10.67%) 3 (0.97%) 0 (0%) 1.13 ± 0.36
Sleepiness 1 (1-4) 215 (69.58%) 68 (22%) 25 (8.09%) 1 (0.32%) 1.39 ± 0.65
Memory problems 2 (1-4) 100 (32.36%) 141 (45.6%) 61 (19.7%) 7 (2.27%) 1.92 ± 0.78
Disturbed sleep 1 (1-4) 188 (60.8%) 89 (28.8%) 30 (9.71%) 2 (0.66%) 1.50 ± 0.70
Overall Score Overall Score 27 (19-49) 28.15 ± 6.24