Key points:
  1. The routine use of LAEP in epilepsy clinics may enhance identification and quantification of adverse effects, and will also help in recognizing persons with epilepsy who are more likely to become depressed, and can be referred for psychiatric evaluation and management.
  2. The most common adverse events were feeling of anger/ aggression (92.9%), nervousness and/or agitation (72.7%), memory problems (67.6%), tiredness (62.5%), headache (54.7%), restlessness (43.6%), hair loss (43.4%), depression (43%) and disturbed sleep (39.2%)
  3. Persons with epilepsy on polytherapy, and those who were positive for depression had higher LAEP score.
  4. At a cut-off of ≥ 28, LAEP can screen persons with epilepsy positive for co-morbid depression as well as monitor the AEs of ASMs.