Conclusions:
MTEM is a rare neoplasm that is associated with radiation therapy,
especially with a long latency period after initial
exposure.10 They are histologically and
immunohistochemically identical to mammary myofibroblastoma.
Radiation-induced neoplasms are rare, but potentially life-threatening
complications of radiotherapy generally requiring aggressive surgery.
This case illustrates successful diagnosis and treatment of a
radiation-induced MTEM in a patient with a history of retinoblastoma
treated by external beam radiation. The neoplasm was removed with
negative margins via partial maxillectomy and total ethmoidectomy
without perioperative complications or local recurrence to date.