Background
Streptococcal toxic shock syndrome (STSS) is a life-threatening infection, which usually leads to rapid deterioration of the patient’s clinical condition. The mortality rate is approximately 30%, with elderly populations showing remarkably worse prognosis [1, 2]. Pyrogenic toxins produced by streptococcus induce hypercytokinemia, leading to development of a shock state. Here, we report a case of STSS due to group G streptococcus (GGS). The patient exhibited necrotizing fasciitis and septic shock with unstable hemodynamics, and was successfully treated with multidisciplinary therapy, including polymyxin B immobilized fiber column direct hemoperfusion (PMX-DHP) and continuous hemodiafiltration (CHDF) using a polyacrylonitrile AN69ST membrane. We obtained the patient’s written informed consent for publication of this case report.