FIGURE 6. Proline-serine-threonine-phosphatase-interacting protein 2 (PSTPIP2) overexpression suppressed AAI-induced tubular epithelial cell PANoptosis.
(A) Western blotting of cleaved-caspase-3, pMLKL, and GSDMD-N. (B) Western blotting of cleaved-caspase-3, pMLKL, and GSDMD-N in mTECs treated with pEX-2-PSTPIP2. (C) Immunofluorescence staining of cleaved-caspase-3, pMLKL, and GSDMD-N in mTECs treated with pEX-2-PSTPIP2 (Scale bar = 100 μm). Data are presented as the mean ± SEM, n = 5. ns, not significant; *P < 0.05, significantly different, as indicated.