Clinical Case n° 1 ( Table 1) (Fig 1)
A 48 year woman, with AAG was refered by Gastroentrology service for evaluation of depigmented patches on her abdomen and legs . Lesions had appeared since 5 years ago . In her past medical history she had diabetes mellitus type I, hypothyroidisim ,pernicious anemia with a positive antiparietal cell antibody and breast cancer. Mastectomy ,chemotherapy and radiotheray had been done for her. Histological description  of gastric mucosa revealed atrophy of parietal cells in fundus and inflammation restricted to the oxyntic mucosa. The disappearing glandular units were replaced by fibrotic expansion of the lamina propria with no changes in the glandular phenotype. We preformed a skin biopsy from the border of the depigmented patch on her right leg .