1.1.2.1. Exosomal lncRNAs and autophagy
Because of the replenishment of energy supply and protection from
environmental stress, cancer cells upregulate autophagy, accordingly,
autophagy is a significant event in cancer [93]. Studies have shown
that because lncRNAs are key regulators of autophagy, they can protect
cancer cells against chemotherapy and environmental stress [88]. In
addition, autophagy induced by lncRNAs has a key role in the
proliferation and survival of tumor cells mediated by CAFs [94].