loading page

Full and simplified assessment of Left Ventricular Diastolic Function in Covid-19 Patients admitted to ICU: feasibility, incidence and association with mortality.
  • +5
  • Luigi La Via,
  • Veronica Dezio,
  • Cristina Santonocito,
  • Marinella Astuto,
  • Andrea Morelli,
  • Stephen J. Huang,
  • Antoine Vieillard-Baron,
  • Filippo Sanfilippo
Luigi La Via
Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Catania
Author Profile
Veronica Dezio
Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Catania
Author Profile
Cristina Santonocito
Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Catania
Author Profile
Marinella Astuto
Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Catania
Author Profile
Andrea Morelli
Universita degli Studi di Roma La Sapienza
Author Profile
Stephen J. Huang
The University of Sydney Nepean Clinical School
Author Profile
Antoine Vieillard-Baron
Hopital Ambroise-Pare
Author Profile
Filippo Sanfilippo
Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Catania
Author Profile

Abstract

Purpose: Left ventricular diastolic dysfunction (LVDD) is associated with poor outcomes in intensive care unit (ICU). Nonetheless, precise reporting of LVDD in COVID-19 patients is currently lacking and assessment could be challenging. Methods: We performed an echocardiography study in COVID-19 patients admitted to ICU with the aim to describe the feasibility of full or simplified LVDD assessment and its incidence. We also evaluated the association of LVDD or of single echocardiographic parameters with hospital mortality. Results: Between 06.10.2020 and 18.02.2021, full diastolic assessment was feasible in 74% (n=26/35) of patients receiving full echocardiogram study. LVDD incidence was 46% (n=12/26), whilst the assessment produced different results (incidence 81%, n=21/26). Nine patients were hospital-survivors (39%); incidence of LVDD (full assessment) was not different between survivors (n=2/9, 22%) and non-survivors (n=10/17, 59%; p=0.11). Also, the E/e’ ratio lateral was lower in survivors (7.4 [3.6] vs non-survivors 10.5 [6.3], p=0.03). We also found that s’ wave was higher in survivors (average, p=0.01). Conclusion: In a small single-center study, assessment of LVDD according to latest guidelines was feasible in three quarter of COVID-19 patients. Non-survivors showed a trend towards greater LVDD incidence; moreover, they had significantly worse s’ values (all) and higher E/e’ ratio (lateral).
13 Jul 2022Submitted to Echocardiography
13 Jul 2022Submission Checks Completed
13 Jul 2022Assigned to Editor
23 Jul 2022Reviewer(s) Assigned
04 Aug 2022Review(s) Completed, Editorial Evaluation Pending
14 Aug 2022Editorial Decision: Revise Major
16 Aug 20221st Revision Received
17 Aug 2022Assigned to Editor
17 Aug 2022Submission Checks Completed
17 Aug 2022Reviewer(s) Assigned
21 Aug 2022Review(s) Completed, Editorial Evaluation Pending
30 Aug 2022Editorial Decision: Revise Minor
03 Sep 20222nd Revision Received
06 Sep 2022Submission Checks Completed
06 Sep 2022Assigned to Editor
07 Sep 2022Reviewer(s) Assigned
08 Sep 2022Review(s) Completed, Editorial Evaluation Pending
09 Sep 2022Editorial Decision: Accept