Figure 4
Dose-dependent effects of pertussis toxin (PTX) on the maximum
inhibition of +10mV-induced calcium currents by NFEPP (a) or fentanyl
(b) at pH 6.5 and pH 7.4 measured by patch clamp in isolated rat sensory
neurons (N=17-22 cells) (left). Effects of the highest PTX doses (Log
µM) (right). ***P < 0.001 PTX vs. control at pH 6.5 vs. 7.4;
2-tailed t test. Data are means ± SEM.