Figure 3
Dose-dependent effects of naloxone on the maximum inhibition of
+10mV-induced calcium currents by NFEPP (a) or fentanyl (b) at pH 6.5
and pH 7.4 measured by patch clamp in isolated rat sensory neurons
(N=16-20 cells) (left). Effects of
the highest naloxone doses (Log µM) (right). ***P < 0.001
naloxone vs. control at pH 6.5 vs 7.4; 2-tailed t test. Data are
means ± SEM.