Figure 7
Effects of inflammatory pH conditions on calcium signals in rat sensory neurons. Fura-2 imaging experiments with rat sensory neurons treated with (a) short (60s) and (b) long (20 min) application of extracellular pH 7.4 (black trace, N=356 neurons), pH 7 (red trace, N=302 neurons), pH 6.5 (green trace, N=383 neurons) and pH 6 (blue trace, N=386 neurons). Twelve recordings for each pH from 4 rats (1 rat per pH) are shown. The right bar graphs represent delta ratio 340/380 for different pH values. P > 0.05; One-way ANOVA on ranks. Traces represent means ± SEM.