The optimal effect-site concentration of remifentanil and propofol for keeping proper anesthesia and promoting early recovery during patient state index-guided anesthesia.

Running head: The optimal concentration of remifentanil and propofol under guidance of patient state index.

Wenjing Han^1#, Tingting Li¹^#, Lianjia Hu², Jiangbing Cao², Jie Shi², Yu Wang³, Zhenxiao Ma³, Jun Li³, Jun Ma³, Sheng Wang^3*

Provincial Hospital Affiliated to Anhui Medical University, Hefei, China.
Anhui Provincial Hospital, Wannan Medical College, Hefei, China.
Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

*Corresponding author: Sheng Wang, Department of Anesthesiology, First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, 17 Lujiang Road, Luyang District, Hefei, 231500, Anhui, China. Tel: +86 191 5600 7726, E-mail: