Conclusion
In conclusion, women with one unLM or ceLM have a poor prognosis,
including a higher risk of miscarriage and a lower live birth rate. This
finding
stressed
the adverse prognostic effect of previous LMs, and
would
impact the reproductive counselling practice in clinics that women with
even only one LM should be informed of the risk and given more intense
surveillance during the subsequent pregnancy. Additionally, further
prospective cohort studies are still needed to verify our finding and
ascertain the mechanisms underlying the reported associations.