The pomegranate is characterized by high nutritional value due to metabolites found in different parts of the plant, such as flowers, leaves, peel, seeds, juice, roots and bark. Sugars (e.g., fructose and glucose), organic acids (e.g., citric acid), dietary fibres, proteins, lipids and bioactive compounds are mainly found in pomegranate (Bar-Ya’akov et al., 2019). Various phytochemicals are present in different parts of the plant and are considered responsible for its therapeutic effects, which are known since antiquity (Longtin, 2003). Phytoestrogens and punicic acid are present in seeds (Shabbir et al., 2017; Zarfeshany et al., 2014) (Fig. 2). The pomegranate is a rich source of polyphenols. The main flavonoids include anthocyanins, luteolin, kaempferol and quercetin. Anthocyanins, which are plant pigments, are found in peel, juice, flowers and leaves. Ellagitannins and gallotannins are hydrolyzable tannins (e.g., punicalagin, ellagic acid, punicalin and gallagic acid) present in every part of the plant (Fig. 3). Alkaloids are mainly found in roots and bark (Bar-Ya’akov et al., 2019; Sreekumar et al., 2014).