Fig.1 Related factors to hyaluronic acid and collagen
The white bar shows the placebo-treated sides and the RSE sides are shown in gray. A) The effect of enhancing HAS2 gene expression was verified by RT-qPCR. The vertical axis shows the HAS2 gene expression ratio to the housekeeping gene GAPDH, and the expression of no sample added was denoted as 1 (negative control). The gene expression ratio when RSE was added is shown. Error bars indicate the standard error. B) The quantitative change in hyaluronic acid produced in the medium by ELISA was verified. The vertical axis shows the concentration of hyaluronic acid (ng/mL) and the error bar shows the standard error. C) The effect of enhanced COL3 gene expression was verified by RT-qPCR. D) The quantitative change in type III collagen produced in the medium by ELISA was verified.