References
1. Matsutani M, Sano K, Takakura K, et al. Primary intracranial germ
cell tumors: a clinical analysis of 153 histologically verified cases.J Neurosurg . 1997;86(3):446-455.
2. Arita N, Ushio Y, Hayakawa T, et al. Serum levels of
alpha-fetoprotein, human chorionic gonadotropin and carcinoembryonic
antigen in patients with primary intracranial germ cell tumors.Oncodev Biol Med . 1980;1(4-5):235-240. Accessed April 9, 2019.
3. Calaminus G, Kortmann R, Worch J, et al. SIOP CNS GCT 96: final
report of outcome of a prospective, multinational nonrandomized trial
for children and adults with intracranial germinoma, comparing
craniospinal irradiation alone with chemotherapy followed by focal
primary site irradiation for pat. Neuro Oncol .
2013;15(6):788-796.
4. Calaminus G, Frappaz D, Kortmann RD, et al. Outcome of patients with
intracranial non-germinomatous germ cell tumors-lessons from the
SIOP-CNS-GCT-96 trial. Neuro Oncol . 2017;19(12):1661-1672.
5. Cole LA. Biological functions of hCG and hCG-related molecules.Reprod Biol Endocrinol . 2010;8:102.
6. Moyle WR, Matzuk MM, Campbell RK, et al. Localization of residues
that confer antibody binding specificity using human chorionic
gonadotropin/luteinizing hormone beta subunit chimeras and mutants.J Biol Chem . 1990;265(15):8511-8518.
7. Goldman S, Bouffet E, Fisher PG, et al. Phase II Trial Assessing the
Ability of Neoadjuvant Chemotherapy With or Without Second-Look Surgery
to Eliminate Measurable Disease for Nongerminomatous Germ Cell Tumors: A
Children’s Oncology Group Study. J Clin Oncol .
2015;33(22):2464-2471.
8. Sawamura Y, Ikeda J, Shirato H, Tada M, Abe H. Germ cell tumours of
the central nervous system: Treatment consideration based on 111 cases
and their long-term clinical outcomes. Eur J Cancer .
1998;34(1):104-110.
9. Takami H, Fukushima S, Fukuoka K, et al. Human chorionic gonadotropin
is expressed virtually in all intracranial germ cell tumors. J
Neurooncol . 2015;124(1):23-32.
10. Fujimaki T, Mishima K, Asai A, et al. Levels of Beta-Human Chorionic
Gonadotropin in Cerebrospinal Fluid of Patients With Malignant Germ Cell
Tumor Can Be Used to Detect Early Recurrence and Monitor the Response to
Treatment. Jpn J Clin Oncol . 2000;30(7):291-294.
11. Matsutani M, Japanese T, Brain P, Study T, Japanese Pediatric Brain
Tumor Study Group. Combined chemotherapy and radiation therapy for CNS
germ cell tumors – the Japanese experience Masao. J Neurooncol .
2001;54(3). Accessed April 9, 2019.
12. Kanda Y. Investigation of the freely available easy-to-use software
“EZR” for medical statistics. Bone Marrow Transplant .
2013;48(3):452-458.
13. Stenman UH, Alfthan H, Hotakainen K. Human chorionic gonadotropin in
cancer. Clin Biochem . 2004;37(7):549-561.
14. Stenman UH, Tiitinen A, Alfthan H, Valmu L. The classification,
functions and clinical use of different isoforms of HCG. Hum
Reprod Update . 2006;12(6):769-784.
15. Willemse PH, Sleijfer DT, Schraffordt Koops H, et al. The value of
AFP and HCG half lives in predicting the efficacy of combination
chemotherapy in patients with non-seminomatous germ cell tumors of the
testis. Oncodev Biol Med . 1981;2(1-2):129-134. Accessed April 30,
2019.
16. Ashitaka Y, Nishimura R, Endoh Y, Tojo S. Subunits of Human
Chorionic Gonadotropin and their Radioimmunoassays. Endocrinol
Jpn . 1974;21(5):429-435.
17. Bristow A, Berger P, Bidart JM, et al. Establishment, value
assignment, and characterization of new WHO reference reagents for six
molecular forms of human chorionic gonadotropin. Clin Chem .
2005;51(1):177-182.
18. Whittington JD, Fantz CR, Gronowski AM, et al. The analytical
specificity of human chorionic gonadotropin assays determined using WHO
International Reference Reagents. Clin Chim Acta .
2010;411(1-2):81-85.
19. Sawamura Y, De Tribolet N, Ishii N, Abe H. Management of primary
intracranial germinomas: Diagnostic surgery or radical resection?J Neurosurg . 1997;87(2):262-266.
20. Takase H, Tanoshima R, Singla N, Nakamura Y, Yamamoto T. Pineal
parenchymal tumor of intermediate differentiation: a systematic review
and contemporary management of 389 cases reported during the last two
decades. Neurosurg Rev . Published online 2021.
21. Saller B, Clara R, Spottl G, Siddle K, Mann K. Testicular cancer
secretes intact human choriogonadotropin (hCG) and its free β-subunit:
Evidence that hCG (+hCG-β) assays are the most reliable in diagnosis and
follow-up. Clin Chem . 1990;36(2):234-239.
22. Fukuoka K, Yanagisawa T, Suzuki T, et al. Human chorionic
gonadotropin detection in cerebrospinal fluid of patients with a
germinoma and its prognostic significance: assessment by using a highly
sensitive enzyme immunoassay. J neurosurg Pediatr .
2016;18(November):573-577.
23. ACOG committee opinion /. Avoiding inappropriate clinical decisions
based on false-positive human chorionic gonadotropin test results.Int J Gynecol Obstet . 2003;80(2):231-233.
24. Rotmensch S, Cole LA. False diagnosis and needless therapy of
presumed malignant disease in women with false-positive human chorionic
gonadotropin concentrations. Lancet . 2000;355(9205):712-715.
25. McCudden CR, Willis MS, Grenache DG. Persistent low concentration of
human chorionic gonadotropin in a nonpregnant woman. Clin Chem .
2008;54(1):209-213; discussion 213-4.
26. Patton PE, Hess DL, Cook DM, Loriaux DL, Braunstein GD. Human
chorionic gonadotropin production by the pituitary gland in a
premenopausal woman. In: American Journal of Obstetrics and
Gynecology . Vol 178. Mosby Inc.; 1998:1138-1142.
27. Braunstein GD, Vaitukaitis JL, Carbone PP, Ross GT. Ectopic
production of human chorionic gonadotrophin by neoplasms. Ann
Intern Med . 1973;78(1):39-45.
28. Gu W, Gu W, Gu Y, et al. A craniopharyngioma associated with
elevated cerebrospinal fluid HCG concentrations misdiagnosed as a
germinoma. Front Neurol . 2018;9(JUN).
29. Louhimo J, Carpelan-Holmström M, Alfthan H, Stenman UH, Järvinen HJ,
Haglund C. Serum HCGβ, CA 72-4 and CEA are independent prognostic
factors in colorectal cancer. Int J Cancer . 2002;101(6):545-548.
30. Vartiainen J, Lassus H, Lehtovirta P, et al. Combination of serum
hCGβ and p53 tissue expression defines distinct subgroups of serous
ovarian carcinoma. Int J Cancer . 2007;122(9):2125-2129.
31. Buckner CL, Wilson L, Papadea CN. An Unusual Cause of Elevated
Serum Total ΒhCG .; 2007.
32. Lempiainen A, Hotakainen K, Blomqvist C, Alfthan H, Stenman UH.
Increased Human Chorionic Gonadotropin Due to Hypogonadism after
Treatment of a Testicular Seminoma. Clin Chem .
2007;53(8):1560-1561.