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His-Optimized Cardiac Resynchronization Therapy (HOT-CRT) in a subcutaneous ICD patient: first-in-human case report
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  • Luca Bontempi,
  • Angelica Fundaliotis,
  • Marina Moretti,
  • Antonino Pitì,
  • Antonio Curnis,
  • Andrea Dell’Aquila
Luca Bontempi
Universita degli Studi di Brescia Dipartimento Specialita Medico-Chirurgiche Scienze Radiologiche e Sanita Pubblica, Azienda Socio Sanitaria Territoriale Bergamo Est
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Angelica Fundaliotis
Azienda Socio Sanitaria Territoriale Bergamo Est
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Marina Moretti
Azienda Socio Sanitaria Territoriale Bergamo Est
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Antonino Pitì
Azienda Socio Sanitaria Territoriale Bergamo Est
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Antonio Curnis
Universita degli Studi di Brescia Dipartimento Specialita Medico-Chirurgiche Scienze Radiologiche e Sanita Pubblica
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Andrea Dell’Aquila
Universita degli Studi di Brescia Dipartimento Specialita Medico-Chirurgiche Scienze Radiologiche e Sanita Pubblica, Azienda Socio Sanitaria Territoriale Bergamo Est

Corresponding Author:[email protected]

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Abstract

Recent developments in arrhythmology have enabled the use of new devices, such as subcutaneous implantable cardioverter-defibrillators (s-ICD), and the comeback of older strategies, such as His-Bundle pacing (HBP) in clinical practice, alongside the use of thoroughly proven therapies such as cardiac resynchronization therapy (CRT), e.g. with His-Optimized CRT (HOT-CRT). However, interplay between these new and older techniques is not always clear. We report the first-in-human case of biventricular pacemaker (CRT-P) implantation with HOT-CRT in an s-ICD patient. Paced QRS morphology was similar to the spontaneous morphology, albeit shorter. Correct QRS identification by the s-ICD was confirmed both intra-procedurally and post-procedurally.