Dual
effect of tacrolimus on mast cell-mediated allergy and inflammation
through MAS-related G
protein-coupled receptor-X2
Xueshan Du1, *, Delu Che1,2, *, Yi
Zheng1, Yong Hao3,1, Tao
Jia1, Xinyue Zhang1,
Bin Peng1, #,
Songmei Geng1,2, #
1 Department of Dermatology, The Second Affiliated
Hospital of Xi’an Jiaotong University, Xi’an, China
2 Center for Dermatology Disease, Precision Medical
Institute, Xi’an, China.
3 Department of Dermatology, The Second Affiliated
Hospital of Baotou Medical College, Baotou, Inner Mongolia, China
*These authors contribute equally to this work
Corresponding author: Bin Peng, Tel: +86 186 2969 1372,1200006589@xjtu.edu.cn;
Songmei Geng, Tel: +86 130 6042 3612, E-mail:gsm312@yahoo.com.
Short title: Tacrolimus regulates MAS-related G protein-coupled
receptor-X2 in allergy and inflammation
Acknowledgement: This work was supported by the National
Natural Science Foundation of China (Grant number: 82073451). And Key
R&D plan of Shaanxi Province (Grant number: 2020SF-175). We also
gratefully acknowledge the support of Research Fund of the Second
Affiliated Hospital of Xi’an Jiaotong University and Chinese Association
of Rehabilitation Medicine (Grant number: D201901).