Method validation
Calibration curve for chemical stability of ointment, emulsion and gel formulations demonstrated linearity with a coeficient of determination (r2) of 0.9998. The limit of detection (LD) and quantification (LQ) were 0.003 and 0.009 mg/ml, respectively. Linearity was determined too for chemical stability of liposomal formulation with a coeficient of determination (r2) of 0.9958, LD= 0.011 mg/ml and LQ= 0.038 mg/ml.