Rapamycin determination
Table 2 shows the rapamycin quantity per weighed formulation quantity
(mg/g) and %CR in each formulation and standard desviation (SD) at
times (t) = 0, 7, 14, 21, 28, 42 and 56 days.
T90 was reached during the sampling period for the
ointment, emulsion and gel formulations: T90=56, 14 and
21 days, respectively. Only liposomes were stable for 56 days.