BMI and BMI Percentile Change by Genotype
In the adult patient group, 35 adults were identified as having the
homozygous F508del genotype, while the other 33 were heterozygous
F508del genotype. In the homozygous genotype group, the mean positive
change in BMI was 1.46 (1.52) kg/m2, while the average
change in the heterozygous group was a gain of 1.49 (1.77)
kg/m2. In the pediatric group, there were 27 children
with the homozygous genotype; they had a mean increase in BMI percentile
of 9.04 (15.83). Eleven children had an F508del heterozygous genotype;
they had an average increase in BMI percentile 6.63 (20.26) percentile.