Conclusion
RI is a frequent phenomenon exist in moderate to severe persistent
asthma children with a history of prematurity or low birth weight, and
it is an indicator of alterations in lung function, especially in the
parameters that evaluate the function of the peripheral airway. In
asthmatics with RI by IOS, it was possible to identify a subgroup with
greater peripheral airway obstruction and less bronchodilator response
than the group in which the RI disappeared after the bronchodilator
test. More studies should be done to confirm these findings.