NS : Not stated. NA : Not applicable
The hospitalization of 78 vaccinated children and adolescents was also investigated. Among the vaccinated pediatrics during the period from April to July, 2021, and according to 6 studies (23-28), for whom clinical data are completed and available, 45 (58%) were hospitalized, and 5 (6.4%) were admitted to ICU. The range of hospital stay for vaccinated pediatrics was found to be 1-6 days.
The difference in clinical symptoms/signs between vaccinated and non-vaccinated pediatrics is shown in Table. 4. Symptoms were found milder in vaccinated pediatrics compared to the diagnosed COVID-19 pediatrics. For instance, none of the vaccinated pediatrics had cough symptoms compared to 51% (150/297) of non-vaccinated pediatrics. Only 32% (25/78) of vaccinated pediatrics had fever compared to 55% (163/297) of the non-vaccinated group. 17% (13/78) had SOB compared to 13% (39/297). 17% (13/78) of vaccinated pediatrics had muscle pain compared to 22% (66/297) for non-vaccinated pediatrics. Headache was only reported in 8% (6/78) compared to 27% (81/297) for the non-vaccinated group. Lastly, 9% (7/78) of the vaccinated group had nausea/vomiting compared to 10% (31/297).
Table 4. Percentage of signs and symptoms among 78 vaccinated pediatric (age<18 years) with BioNTech-Pfizer vaccine and 297 non-vaccinated pediatric (age<18 years, Lab confirmed COVID-19) in North America.