Conclusion
Humankind and the entire world are still suffering from the third coronavirus infection (SARS-CoV-2), causing severe acute respiratory syndrome and bringing countless morbidity, mortality, and a great economic disaster. With the new Delta andOmicron variants of this coronavirus, more preventive measures and procedures, including more vaccinations for children and adolescents, are crucial and highly recommended to reduce the transmission, hospitalization, and adverse clinical outcomes. Although we found good outcomes and statistically significant associations in symptoms between vaccinated and non-vaccinated pediatrics, more studies are still crucial to understand the specific etiology further underlying post-vaccination, particularly myocarditis, psychological impact, and other cardiac clinical symptoms on children and adolescents after receiving the BioNTech-Pfizer vaccine.