Methods
A systematic review was conducted in accordance with the Preferred
Reporting Items for Systematic Reviews (PRISMA) guidelines (22), a
comprehensive search was performed in PubMed, Scopus, MEDLINE, and
EMBASE Databases for research publications on COVID-19 published between
December 2019 and October 2021 using the terms COVID-19, Pediatrics,
children, adolescents, SARS-CoV-2, Epidemiology, and Vaccine. Phrases
used for the Medical Subject Heading [MeSH] search included:
(((“COVID-19” [MeSH]) and “Vaccine” [MeSH]) and “Children”
[MeSH]) and “adolescents” [MeSH]) and “Pfizer” [MeSH].
We focused on original research, case reports, case series, and
vaccination side-effect by authoritative health institutions. All
records were retrieved, including original articles, letters to the
editor, editorials, and case reports, in English, and records with
English translation were downloaded and reviewed. Given the current
scarcity of evidence, preprints, in-press papers, and
accepted-for-publication research were also considered.